Systemic lupus erythematosus and cardiovascular disease

J Frostegård - Journal of Internal Medicine, 2023 - Wiley Online Library
The prognosis in systemic lupus erythematosus (SLE) has improved due to better treatment
and care, but cardiovascular disease (CVD) still remains an important clinical problem, since …

Antibodies against phosphorylcholine and protection against atherosclerosis, cardiovascular disease and chronic inflammation

J Frostegård - Expert Review of Clinical Immunology, 2022 - Taylor & Francis
Introduction Chronic inflammatory diseases include cardiovascular disease (CVD),
atherosclerosis, rheumatic and autoimmune diseases, and others, constituting a large part of …

Formerly bile-farmed bears as a model of accelerated ageing

SK Kalogeropoulu, H Rauch-Schmücking, EJ Lloyd… - Scientific Reports, 2023 - nature.com
Bear bile-farming is common in East and Southeast Asia and this farming practice often
results in irreversible health outcomes for the animals. We studied long-term effects of …

Antibodies in action: the role of humoral immunity in the fight against atherosclerosis

JA Taylor, MA Hutchinson, PJ Gearhart, RW Maul - Immunity & Ageing, 2022 - Springer
The sequestering of oxidation-modified low-density lipoprotein by macrophages results in
the accumulation of fatty deposits within the walls of arteries. Necrosis of these cells causes …

Antibodies against Phosphorylcholine—Implications for Chronic Inflammatory Diseases

J Frostegård - Metabolites, 2023 - mdpi.com
Atherosclerosis and its main consequence, cardiovascular disease (CVD) are nowadays
regarded as chronic inflammatory disease conditions, and CVD is the main cause of death …

[HTML][HTML] Antibodies against phosphorylcholine among 60-year-olds: Clinical role and simulated interactions

SK Samal, PK Panda, M Vikström, K Leander… - Frontiers in …, 2022 - frontiersin.org
Aims Antibodies against phosphorylcholine (anti-PC) are implicated as protection markers in
atherosclerosis, cardiovascular disease (CVD), and other chronic inflammatory conditions …

Antibodies against malondialdehyde among 60-year-olds: prediction of cardiovascular disease

SK Samal, K Leander, M Vikström, L Griesbaum… - Scientific Reports, 2023 - nature.com
Malondialdehyde (MDA) is generated in oxidized LDL. It forms covalent protein adducts, and
is recognized by antibodies (anti-MDA). We previously studied IgM anti-MDA, and here we …

Synthetic biology: refining human health

SK Samal, S Preetam - Microbial Engineering for Therapeutics, 2022 - Springer
Scientists of various disciplines and backgrounds collaborate to conceive and design
revolutionary biomolecular components, networks, and pathways, after which they use these …

[PDF][PDF] Serum plays an important role in reprogramming the seasonal transcriptional profile of brown bear adipocytes

MW Saxton, BW Perry, BDE Hutzenbiler, S Trojahn… - Iscience, 2022 - cell.com
Understanding how metabolic reprogramming happens in cells will aid the progress in the
treatment of a variety of metabolic disorders. Brown bears undergo seasonal shifts in insulin …

[PDF][PDF] Biomimetics and planetary health–a review of human diseases in interaction with the environment and ecosystem

P Stenvinkel - Danish Medical Journal, 2023 - content.ugeskriftet.dk
Elderly people and patients with chronic lifestyle diseases are at risk of being hit harder by
environmental influences. Environmental impacts increase the risk of various lifestyle …