Immunopathogenesis of membranous nephropathy: an update

H Debiec, P Ronco - Seminars in immunopathology, 2014 - Springer
Membranous nephropathy (MN) is a non-inflammatory organ-specific autoimmune disease
which affects the kidney glomerulus, resulting in the formation of immune deposits on the …

[HTML][HTML] Emerging technologies in autoantibody testing for rheumatic diseases

NJ Olsen, MY Choi, MJ Fritzler - Arthritis Research & Therapy, 2017 - Springer
Testing for the presence of antinuclear antibodies (ANAs) is a key step in the diagnosis of
systemic lupus erythematosus (SLE) and other systemic autoimmune rheumatic diseases …

[HTML][HTML] Novel ELISA for thrombospondin type 1 domain-containing 7A autoantibodies in membranous nephropathy

C Zaghrini, B Seitz-Polski, J Justino, G Dolla, C Payre… - Kidney International, 2019 - Elsevier
Autoantibodies against phospholipase A2 receptor 1 (PLA2R1) and thrombospondin type 1
domain-containing 7A (THSD7A) are emerging as biomarkers to classify membranous …

Diagnostic specificity of autoantibodies to M-type phospholipase A2 receptor (PLA2R) in differentiating idiopathic membranous nephropathy (IMN) from secondary …

A Radice, F Pieruzzi, B Trezzi, G Ghiggeri… - Journal of …, 2018 - Springer
Autoantibody against phospholipase A2 receptor (anti-PLA2R) is a sensitive and specific
biomarker of idiopathic membranous nephropathy (iMN), being found in approximately 70 …

[HTML][HTML] Diagnostic accuracy of PLA2R autoantibodies and glomerular staining for the differentiation of idiopathic and secondary membranous nephropathy: an …

H Dai, H Zhang, Y He - Scientific reports, 2015 - nature.com
The diagnostic performance of M-type phospholipase A2 receptor (PLA2R) autoantibodies
and PLA2R glomerular staining in discriminating between idiopathic membranous …

Antibodies to M-type phospholipase A2 receptor (PLA2R) in membranous lupus nephritis

E Garcia-Vives, C Solé, T Moliné, AM Alvarez-Rios… - Lupus, 2019 - journals.sagepub.com
Background Antibodies to M-type phospholipase A2 receptor (a-PLA2R) have been
identified in most patients with idiopathic membranous nephropathy, but the prevalence in …

[HTML][HTML] Novel biomarkers in membranous nephropathy

Q Liu, J Liu, B Lin, Y Zhang, M Ma, M Yang… - Frontiers in …, 2022 - frontiersin.org
Membranous nephropathy (MN) is the main cause of adult nephrotic syndrome (NS). The
pathogenesis of MN is complex and involves subepithelial immune complex deposition …

IgG4 anti-phospholipase A2 receptor might activate lectin and alternative complement pathway meanwhile in idiopathic membranous nephropathy: an inspiration from …

Y Yang, C Wang, L Jin, F He, C Li, Q Gao, G Chen… - Immunologic …, 2016 - Springer
The deposition of IgG4 of antibodies against phospholipase A2 receptor (anti-PLA 2 R) is
predominating in the kidneys of patients with idiopathic membranous nephropathy, while its …

[HTML][HTML] Definition of IgG subclass-specific glycopatterns in idiopathic membranous nephropathy: Aberrant IgG glycoforms in blood

C Chinello, N de Haan, G Capitoli, B Trezzi… - International Journal of …, 2022 - mdpi.com
The podocyte injury, and consequent proteinuria, that characterize the pathology of
idiopathic membranous nephropathy (IMN) is mediated by an autoimmune reaction against …

[HTML][HTML] Diagnostic accuracy of anti-phospholipase A2 receptor (PLA2R) antibodies in idiopathic membranous nephropathy: an Italian experience

B Porcelli, A Guarnieri, F Ferretti, G Garosi… - Journal of …, 2021 - Springer
Background Autoantibodies against-phospholipase A2 receptor (PLA2R) are specific
markers of idiopathic membranous nephropathy (iMN). Enzyme-linked immunosorbent …