Role of surgical intervention in unresectable non-small cell lung cancer

S Suzuki, T Goto - Journal of Clinical Medicine, 2020 - mdpi.com
With the development of systemic treatments with high response rates, including tyrosine
kinase inhibitors and immune checkpoint inhibitors, some patients with unresectable lung …

Surgical resection of advanced non-small cell lung cancer after a response to EGFR-TKI: presentation of two cases and a literature review

Y Yamamoto, K Kodama, T Maniwa… - Journal of Cardiothoracic …, 2017 - Springer
Background The usefulness of residual tumor resection after epidermal growth factor
receptor tyrosine kinase inhibitor (EGFR-TKI) treatment remains unclear. We describe two …

Salvage surgery for non-small cell lung cancer after tyrosine kinase inhibitor treatment

Y Ohtaki, K Shimizu, H Suzuki, K Suzuki, M Tsuboi… - Lung Cancer, 2021 - Elsevier
Objectives The prognostic impact of surgical intervention for recurrent or residual non-small
cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) mutation or …

Outcomes of salvage lung resections in advanced EGFR‐mutant lung adenocarcinomas under EGFR TKIs

YY Chen, YT Yen, WW Lai, WL Huang… - Thoracic …, 2021 - Wiley Online Library
Background Studies regarding the outcomes of salvage lung resections of epidermal growth
factor receptor (EGFR)‐mutant advanced lung adenocarcinomas (ALAs) following treatment …

[HTML][HTML] Salvage surgery after first-line alectinib for locally-advanced/metastatic ALK-rearranged NSCLC: pathological response and perioperative results

F Lococo, A Cancellieri, M Chiappetta, A Leonetti… - Clinical Lung Cancer, 2023 - Elsevier
Background The role of salvage surgery after tyrosine kinase inhibitors in advanced
oncogene-addicted non-small cell lung cancer is largely unexplored. Patients We aimed to …

Continued EGFR-TKI with concurrent radiotherapy to improve time to progression (TTP) in patients with locally progressive non-small cell lung cancer (NSCLC) after …

Y Wang, Y Li, L Xia, K Niu, X Chen, D Lu… - Clinical and …, 2018 - Springer
Background Epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) is the
optimal treatment for EGFR-mutant advanced non-small cell lung cancer (NSCLC) …

[HTML][HTML] 射频消融在EGFR-TKIs 治疗非小细胞肺癌后局部进展的初步临床应用

刘宝东, 李元博, 胡牧, 刘磊, 钱坤… - Chinese Journal of Lung …, 2016 - ncbi.nlm.nih.gov
背景与目的表皮生长因子受体酪氨酸激酶抑制剂(epidermal growth factor receptor-tyrosine
kinase inhibitors, EGFR-TKIs) 是EGFR 敏感突变非小细胞肺癌患者的主要治疗手段之一 …

Safety and efficacy of salvage surgery for non-small cell lung cancer: a retrospective study of 46 patients from four Keio-affiliated hospitals

S Suzuki, K Asakura, M Okui, M Sawafuji… - General thoracic and …, 2022 - Springer
Objectives Advances in drug therapy and radiotherapy for non-small cell lung cancer
resulted in an increased number of salvage surgeries for initially unresectable tumors. This …

[HTML][HTML] Radical surgical resection after neoadjuvant targeted therapy in non-small cell lung cancer: a single-center retrospective study of 6 cases

Z Zhang, J Lin, S Peng, W Lin… - Journal of thoracic disease, 2019 - ncbi.nlm.nih.gov
With the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) recurrence,
gefitinib is the first targeted drug to be approved for advanced non-small cell lung cancer …

Thoracic surgery improved overall survival in patients with stage IIIB–IV epidermal growth factor receptor-mutant lung adenocarcinoma who received and responded …

YN Chien, YC Lin, CL Chang, WC Lin, SY Wu - Lung Cancer, 2021 - Elsevier
Purpose No large-scale, prospective, randomized study has evaluated the effect of thoracic
surgery on patients with unresectable stage IIIB–IV epidermal growth factor receptor (EGFR) …