In 2015, oncolytic virotherapy was approved for clinical use, and in 2017, recombinant
adeno-associated virus (AAV) delivery was also approved. However, systemic …

The cellular stress and immunity cycle is a cornerstone of organismal homeostasis. Stress
activates intracellular and intercellular communications within a tissue or organ to initiate …

Oncolytic viruses (OVs) are emerging as potential treatment options for cancer. Natural and
genetically engineered viruses exhibit various antitumor mechanisms. OVs act by direct …

Pancreatic cancer remains one of the deadliest cancers with extremely high mortality rate,
and the number of cases is expected to steadily increase with time. Pancreatic cancer is …

The interplay between extracellular matrix (ECM) stiffness and the tumor microenvironment
is increasingly recognized as a critical factor in cancer progression and the efficacy of …

The diverse bacterial populations within the symbiotic microbiota play a pivotal role in both
health and disease. Microbiota modulates critical aspects of tumor biology including cell …

Since their discovery, cancer stem cells have become a hot topic in cancer therapy research.
These cells possess stem cell-like self-renewal and differentiation capacities and are …

Background Tumors of the gastrointestinal tract impose a substantial healthcare burden due
to their prevalence and challenging prognosis. Methods We conducted a review of peer …

Adenoviral vectors have been widely used as vaccine candidates or potential vaccine
candidates against infectious diseases due to the convenience of genome manipulation …

Most human malignancies are attributed to exposure to infectious organisms such as
viruses. Certain infections that can induce cancer can evade the immune system, leading to …