The process of spermatogenesis is temperature-dependent and occurs optimally at
temperatures slightly lower than that of the body. Adequate thermoregulation is imperative to …

The mechanisms responsible for producing abnormal spermatozoa in the ejaculate are
relatively unknown. Numerous studies have now shown the presence of nuclear DNA strand …

An investigation was undertaken to determine whether the germ‐ceil loss associated with
exposure of the testis to abdominal temperature occurs by apoptosis. Using an adult‐mouse …

Testis torsion-induced aspermatogenesis is not necessarily due to permanent loss of blood
flow nor to dysfunctional Leydig cells or Sertoli cells. This investigation was undertaken to …

The present study was designed to clarify the role of radical oxygen species in testicular
germ cell apoptosis induced by heat stress. Testicular cells isolated from immature rats were …

Recent work has implicated nitric oxide (NO) in several aspects of male genital physiology
including erectile function and androgen secretion, as well as in vitro effects on sperm …

The vast majority of mammalian testes are located outside the body cavity for proper
thermoregulation. Heat has an adverse effect on mammalian spermatogenesis and …

To investigate apoptotic changes, we studied the cleavage of DNA in the uterine
endometrium obtained from regularly cycling women by a quantitative end labeling of DNA …

Accumulating evidence from animal and hu-man studies has demonstrated that varicoceles
are associated with a time-dependent decline in testicular function. 1–4 As a result, the …

More than half of differentiating spermatogenic cells undergo apoptosis before maturing into
spermatozoa during mammalian spermatogenesis. These cells are selectively and rapidly …