Saturated Fats and Health: A Reassessment and Proposal for Food-Based Recommendations: JACC State-of-the-Art Review

A Astrup, F Magkos, DM Bier, JT Brenna… - Journal of the American …, 2020 - jacc.org
The recommendation to limit dietary saturated fatty acid (SFA) intake has persisted despite
mounting evidence to the contrary. Most recent meta-analyses of randomized trials and …

Intake of saturated and trans unsaturated fatty acids and risk of all cause mortality, cardiovascular disease, and type 2 diabetes: systematic review and meta-analysis …

RJ De Souza, A Mente, A Maroleanu, AI Cozma, V Ha… - Bmj, 2015 - bmj.com
Objective To systematically review associations between intake of saturated fat and trans
unsaturated fat and all cause mortality, cardiovascular disease (CVD) and associated …

[HTML][HTML] Impact of α-linolenic acid, the vegetable ω-3 fatty acid, on cardiovascular disease and cognition

A Sala-Vila, J Fleming, P Kris-Etherton, E Ros - Advances in Nutrition, 2022 - Elsevier
Given the evidence of the health benefits of plant-based diets and long-chain n–3 (ω-3) fatty
acids, there is keen interest in better understanding the role of α-linolenic acid (ALA), a plant …

Biomarkers of dietary omega-6 fatty acids and incident cardiovascular disease and mortality: an individual-level pooled analysis of 30 cohort studies

M Marklund, JHY Wu, F Imamura, LC Del Gobbo… - Circulation, 2019 - Am Heart Assoc
Background: Global dietary recommendations for and cardiovascular effects of linoleic acid,
the major dietary omega-6 fatty acid, and its major metabolite, arachidonic acid, remain …

[HTML][HTML] Gas chromatography-mass spectrometry-based analytical strategies for fatty acid analysis in biological samples

HH Chiu, CH Kuo - Journal of food and drug analysis, 2020 - Elsevier
Fatty acids play critical roles in biological systems. Imbalances in fatty acids are related to a
variety of diseases, which makes the measurement of fatty acids in biological samples …

Comprehensive profiling of plasma fatty acid concentrations in young healthy Canadian adults

SA Abdelmagid, SE Clarke, DE Nielsen, A Badawi… - PloS one, 2015 - journals.plos.org
Circulating fatty acids (FA) are associated with a multitude of chronic diseases. However, a
major gap in establishing such relationships is the lack of accepted fatty acid reference …

Omega-3 polyunsaturated fatty acid biomarkers and risk of type 2 diabetes, cardiovascular disease, cancer, and mortality

H Jiang, L Wang, D Wang, N Yan, C Li, M Wu, F Wang… - Clinical Nutrition, 2022 - Elsevier
Background & aims Considerable attention has focused on the role of omega-3
polyunsaturated fatty acids (PUFA) in the prevention of cardiometabolic diseases, which has …

Intake and metabolism of omega-3 and omega-6 polyunsaturated fatty acids: nutritional implications for cardiometabolic diseases

MB Schulze, AM Minihane, RNM Saleh… - The Lancet Diabetes & …, 2020 - thelancet.com
Prospective observational studies support the use of long-chain omega-3 polyunsaturated
fatty acids (PUFAs) in the primary prevention of atherosclerotic cardiovascular disease; …

[HTML][HTML] Biomarkers of dairy fat intake, incident cardiovascular disease, and all-cause mortality: A cohort study, systematic review, and meta-analysis

K Trieu, S Bhat, Z Dai, K Leander, B Gigante… - PLoS …, 2021 - journals.plos.org
Background We aimed to investigate the association of serum pentadecanoic acid (15: 0), a
biomarker of dairy fat intake, with incident cardiovascular disease (CVD) and all-cause …

Saturated fatty acid biomarkers and risk of cardiometabolic diseases: a meta-analysis of prospective studies

Z Li, H Lei, H Jiang, Y Fan, J Shi, C Li, F Chen… - Frontiers in …, 2022 - frontiersin.org
Background and aims Evidence regarding associations of circulating saturated fatty acids
(SFAs) with chronic diseases is mixed. The objective of this study was to determine the …