Protein phosphorylation controls many aspects of cell fate and is often deregulated in
pathological conditions. Several recent findings have provided an intriguing insight into the …

Spinal cord injury (SCI) is a severely disabling central nervous system injury with complex
pathological mechanisms that leads to sensory and motor dysfunction. The current treatment …

Phosphoinositides are membrane-bound signalling molecules that regulate cell proliferation
and survival, cytoskeletal reorganization and vesicular trafficking by recruiting effector …

The regulation of neuronal differentiation and neurite outgrowth is essential during
development of the nervous system and is crucial in developing therapies to promote axon …

A critical transition in neuron development is formation of the axon, which establishes the
polarized structure of the neuron that underlies its entire input and output capabilities. The …

Dendrite morphology is pivotal for neural circuitry functioning. While the causative
relationship between small-scale dendrite morphological abnormalities (shape, density of …

γ-Enolase, a glycolytic enzyme, is expressed specifically in neurons. It exerts neurotrophic
activity and has been suggested to regulate growth, differentiation, survival and …

A national treasure mushroom, Lignosus rhinocerus, has been used to treat variety of
ailments by local and indigenous communities in Malaysia. The aim of this study was to …

The glutamate-induced excitotoxicity pathway has been reported in several
neurodegenerative diseases. Molecules that inhibit the release of glutamate or cause the …

Background Drugs dedicated to alleviate neurodegenerative diseases like Parkinson's and
Alzheimer's have always been associated with debilitating side effects. Medicinal …