Endocytosis is a critical mechanism providing not only internalization of biomacromolecular
structures but also communication with the environment where cells reside. Due to being the …

During an initial phase of kidney stone formation, the internalization of calcium oxalate
(CaOx) crystals by renal tubular cells has been thought to occur via endocytosis. However …

Much data in the scientific literature demonstrate a fundamental involvement of caveolae in
insulin action, although particular aspects remain matters of debate. The insulin receptor …

Selectively targeting the cell nucleolus remains a challenge. Here, we report the first case in
which d-peptides form membraneless molecular condensates with RNA for targeting cell …

Adipocytes play an important role in the insulin-dependent regulation of organismal fuel
metabolism and express caveolae at levels as high or higher than any other cell type …

It has been known for decades that the adipocyte cell surface is particularly rich in small
invaginations we now know to be caveolae. These structures are common to many cell types …

Insulin stimulates glucose uptake in adult skeletal muscle by promoting the translocation of
GLUT4 glucose transporters to the transverse tubule (T-tubule) membranes, which have …

Clathrin-mediated endocytosis has been described as the primary internalization pathway
for many viruses, including the influenza virus. However, caveolae, an alternative clathrin …

ABSTRACT GLUT4 (also known as SLC2A4) is essential for glucose uptake in skeletal
muscles and adipocytes, which play central roles in whole-body glucose metabolism. Here …

We previously showed that ENaC is present in lipid rafts in A6 cells, a Xenopus kidney cell
line. We now demonstrate that ENaC can be detected in lipid rafts in mouse cortical …