The adipokine Neuregulin 4 (Nrg4) protects against obesity-induced insulin resistance.
Here, we analyze how the downregulation of Nrg4 influences insulin action and the …

The voltage-dependent potassium channel Kv1. 3 plays essential physiological functions in
the immune system. Kv1. 3, regulating the membrane potential, facilitates downstream Ca2+ …

Lipopolysaccharide (LPS) induces inflammatory activation through TLR4 (toll-like receptor-
4)/MD-2 (myeloid differentiation-2)/CD14 (cluster of differentiation-14) complex. Although …

Human milk contains extracellular vesicles (HMEVs). Pre‐clinical models suggest that
HMEVs may enhance intestinal function and limit inflammation; however, it is unknown if …

The intracellular protein corona has not been fully investigated in the field of
nanotechnology-biology (nano-bio) interactions. To effectively understand intracellular …

The facilitative glucose transporter GLUT4, a recycling membrane protein, is required for
dietary glucose uptake into muscle and fat cells. GLUT4 is also responsible for the increased …

To investigate the potential role of phosphatidylinositol 4, 5-bisphosphate (PI (4, 5) P 2) in
the regulation of actin polymerization and GLUT4 translocation, the type I …

Increased hepatocyte growth factor receptor (HGFR) signaling correlates closely with
neoplastic invasion and metastatic potential of many human cancers. Hepatocyte growth …

Insulin and contraction stimulate both cardiac glucose and long-chain fatty acid (LCFA)
uptake via translocation of the substrate transporters GLUT4 and CD36, respectively, from …

Caveolae are the primary route for internalization and transendothelial transport of
macromolecules, such as insulin and albumin. Caveolae-mediated endocytosis is activated …