The controversial relationship between benign prostatic hyperplasia and prostate cancer: the role of inflammation

C De Nunzio, G Kramer, M Marberger, R Montironi… - European urology, 2011 - Elsevier
Abstract Context Prostate cancer (PCa) is the most common cancer in the adult male, and
benign prostatic hyperplasia (BPH) represents the most frequent urologic diagnosis in …

The correlation between metabolic syndrome and prostatic diseases

C De Nunzio, W Aronson, SJ Freedland… - European urology, 2012 - Elsevier
CONTEXT: Metabolic syndrome (MetS), a cluster of several metabolic abnormalities with a
high socioeconomic cost, is considered a worldwide epidemic. Recent epidemiologic and …

The role of chronic prostatic inflammation in the pathogenesis and progression of benign prostatic hyperplasia (BPH).

G Gandaglia, A Briganti, P Gontero… - BJU …, 2013 - search.ebscohost.com
Several different stimuli may induce chronic prostatic inflammation, which in turn would lead
to tissue damage and continuous wound healing, thus contributing to prostatic enlargement …

Oxidative stress in prostate hyperplasia and carcinogenesis

UK Udensi, PB Tchounwou - Journal of Experimental & Clinical Cancer …, 2016 - Springer
Prostatic hyperplasia (PH) is a common urologic disease that affects mostly elderly men. PH
can be classified as benign prostatic hyperplasia (BPH), or prostate cancer (PCa) based on …

The link between benign prostatic hyperplasia and prostate cancer

DD Ørsted, SE Bojesen - Nature Reviews Urology, 2013 - nature.com
Benign prostatic hyperplasia (BPH) and prostate cancer are among the most common
diseases of the prostate gland and represent significant burdens for patients and health-care …

Computer simulations suggest that prostate enlargement due to benign prostatic hyperplasia mechanically impedes prostate cancer growth

G Lorenzo, TJR Hughes… - Proceedings of the …, 2019 - National Acad Sciences
Prostate cancer and benign prostatic hyperplasia are common genitourinary diseases in
aging men. Both pathologies may coexist and share numerous similarities, which have …

Association of 5α-reductase inhibitors with prostate cancer mortality

L Björnebo, T Nordström, A Discacciati… - JAMA …, 2022 - jamanetwork.com
Importance There is evidence that 5α-reductase inhibitors (5-ARIs), a standard treatment of
benign prostate hyperplasia, are associated with a decrease in the incidence of prostate …

Benign prostatic hyperplasia and the risk of prostate cancer and bladder cancer: a meta-analysis of observational studies

X Dai, X Fang, Y Ma, J Xianyu - Medicine, 2016 - journals.lww.com
Benign Prostatic Hyperplasia and the Risk of Prostate Cancer... : Medicine Benign Prostatic
Hyperplasia and the Risk of Prostate Cancer and Bladder Cancer: A Meta-Analysis of …

The crosstalk between prostate cancer and microbiota inflammation: nutraceutical products are useful to balance this interplay?

F Crocetto, M Boccellino, B Barone, E Di Zazzo… - Nutrients, 2020 - mdpi.com
The human microbiota shows pivotal roles in urologic health and disease. Emerging studies
indicate that gut and urinary microbiomes can impact several urological diseases, both …

Biomarkers that differentiate benign prostatic hyperplasia from prostate cancer: A literature review

CJ McNally, MW Ruddock, T Moore… - Cancer management …, 2020 - Taylor & Francis
Prediction of prostate cancer in primary care is typically based upon serum total prostate-
specific antigen (tPSA) and digital rectal examination results. However, these tests lack …