Assessing the co-variability of DNA methylation across peripheral cells and tissues: Implications for the interpretation of findings in epigenetic epidemiology
Most epigenome-wide association studies (EWAS) quantify DNA methylation (DNAm) in
peripheral tissues such as whole blood to identify positions in the genome where variation is …
peripheral tissues such as whole blood to identify positions in the genome where variation is …
Modeling genome-wide by environment interactions through omnigenic interactome networks
H Wang, M Ye, Y Fu, A Dong, M Zhang, L Feng, X Zhu… - Cell Reports, 2021 - cell.com
How genes interact with the environment to shape phenotypic variation and evolution is a
fundamental question intriguing to biologists from various fields. Existing linear models built …
fundamental question intriguing to biologists from various fields. Existing linear models built …
Clinical validation of a blood-based predictive test for stratification of response to tumor necrosis factor inhibitor therapies in rheumatoid arthritis patients
T Mellors, JB Withers, A Ameli, A Jones… - Network and Systems …, 2020 - liebertpub.com
Objectives: For rheumatoid arthritis (RA) patients failing to achieve treatment targets with
conventional synthetic disease-modifying antirheumatic drugs, tumor necrosis factor (TNF)-α …
conventional synthetic disease-modifying antirheumatic drugs, tumor necrosis factor (TNF)-α …
Modeling interaction and dispersion effects in the analysis of gene-by-environment interaction
Genotype-by-environment interaction (GxE) studies probe heterogeneity in response to risk
factors or interventions. Popular methods for estimation of GxE examine multiplicative …
factors or interventions. Popular methods for estimation of GxE examine multiplicative …
High‐Performance Ambipolar and n‐Type Emissive Semiconductors Based on Perfluorophenyl‐Substituted Perylene and Anthracene
L Chen, Z Qin, H Huang, J Zhang, Z Yin, X Yu… - Advanced …, 2023 - Wiley Online Library
Emissive organic semiconductors are highly demanding for organic light‐emitting transistors
(OLETs) and electrically pumped organic lasers (EPOLs). However, it remains a great …
(OLETs) and electrically pumped organic lasers (EPOLs). However, it remains a great …
Telecom‐Wavelength Organic Single‐Crystal Lasers Triggered by the Molecular Conformation‐Dependent Cascaded Proton Transfer Processes
JJ Wu, S Yu, Y Liu, CC Yan, WY Yang… - Advanced Functional …, 2023 - Wiley Online Library
Organic semiconductor molecules possess chemical tunability and large stimulated
emission cross section, representing a promising candidate for laser gain medium …
emission cross section, representing a promising candidate for laser gain medium …
Rippling ferroic phase transition and domain switching in 2D materials
Ripples are a class of native structural defects widely existing in 2D materials. They originate
from the out‐of‐plane flexibility of 2D materials introducing spatially evolving electronic …
from the out‐of‐plane flexibility of 2D materials introducing spatially evolving electronic …
Gene-environment interactions for cardiovascular disease
JA Hartiala, JR Hilser, S Biswas, AJ Lusis… - Current atherosclerosis …, 2021 - Springer
Abstract Purpose of Review We provide an overview of recent findings with respect to gene-
environment (GxE) interactions for cardiovascular disease (CVD) risk and discuss future …
environment (GxE) interactions for cardiovascular disease (CVD) risk and discuss future …
Ferroelastic–ferroelectric multiferroicity in van der Waals rhenium dichalcogenides
Abstract 2D multiferroics with combined ferroic orders have gained attention owing to their
novel functionality and underlying science. Intrinsic ferroelastic–ferroelectric multiferroicity in …
novel functionality and underlying science. Intrinsic ferroelastic–ferroelectric multiferroicity in …
Admixed populations improve power for variant discovery and portability in genome-wide association studies
Genome-wide association studies (GWAS) are primarily conducted in single-ancestry
settings. The low transferability of results has limited our understanding of human genetic …
settings. The low transferability of results has limited our understanding of human genetic …