An animal model to study human infectious diseases should accurately reproduce the
various aspects of disease. Domestic pigs (Sus scrofa domesticus) are closely related to …

Traditional biomedical models are easy to manage in experimental facilities and allow fast
and affordable basic genetic studies related to human disorders, but in some cases they do …

We report the sequencing at 131× coverage, de novo assembly and analyses of the genome
of a female Tibetan wild boar. We also resequenced the whole genomes of 30 Tibetan wild …

The translation of novel discoveries from basic research to clinical application is a long,
often inefficient, and thus costly process. Accordingly, the process of drug development …

Livestock plays a central role in sustaining human livelihood in South Asia. There are
numerous and distinct livestock species in South Asian countries. Several of them have …

Uncovering genetic variation through resequencing is limited by the fact that only sequences
with similarity to the reference genome are examined. Reference genomes are often …

Airway disease currently causes most of the morbidity and mortality in patients with cystic
fibrosis (CF). However, understanding the pathogenesis of CF lung disease and developing …

Background Pigs were domesticated independently in Eastern and Western Eurasia early
during the agricultural revolution, and have since been transported and traded across the …

The conservation of farm animal resources is important for coping with future breeding
needs and for facilitating the sustainable use of marginal areas. The increasing availability …

Large animals (non-human primates, livestock and dogs) are playing important roles in
biomedical research, and large livestock animals serve as important sources of meat and …