Kinase inhibitors of marine origin

SB Bharate, SD Sawant, PP Singh… - Chemical …, 2013 - ACS Publications
The ocean occupies three-fourths of the Earth's surface and hosts approximately 80% of all
living species. In fact, some areas of the sea such as coral reefs possess a biodiversity …

A renaissance in marine pharmacology: from preclinical curiosity to clinical reality

KB Glaser, AMS Mayer - Biochemical pharmacology, 2009 - Elsevier
Marine pharmacology, the pharmacology of marine natural products, has been for some
time more associated with marine natural products chemistry rather than mainstay …

Discorhabdins and pyrroloiminoquinone-related alkaloids

JF Hu, H Fan, J Xiong, SB Wu - Chemical reviews, 2011 - ACS Publications
Alkaloids, such as lamellarins1 and manzamines, 2 with complex structures and promising
biological activities produced by marine plants, invertebrates and microbes have greatly …

Merging the potential of microbial genetics with biological and chemical diversity: an even brighter future for marine natural product drug discovery

CE Salomon, NA Magarvey, DH Sherman - Natural product reports, 2004 - pubs.rsc.org
Covering: 1999–2003Marine invertebrates and a growing number of marine bacteria are the
sources of novel, bioactive secondary metabolites. Structurally, many of these compounds …

Culturable Actinobacteria from the Marine Sponge Hymeniacidon perleve: Isolation and Phylogenetic Diversity by 16S rRNA gene-RFLP Analysis

H Zhang, YK Lee, W Zhang, HK Lee - Antonie Van Leeuwenhoek, 2006 - Springer
A total of 106 actinobacteria associated with the marine sponge Hymeniacidon perleve
collected from the Yellow Sea, China were isolated using eight different media. The number …

Antimicrobial peptides from marine proteobacteria

F Desriac, C Jégou, E Balnois, B Brillet, P Le Chevalier… - Marine drugs, 2013 - mdpi.com
After years of inadequate use and the emergence of multidrug resistant (MDR) strains, the
efficiency of “classical” antibiotics has decreased significantly. New drugs to fight MDR …

Volatile halogenated metabolites from marine red algae

M Kladi, C Vagias, V Roussis - Phytochemistry Reviews, 2004 - Springer
A significant number of halogenated low molecular weight metabolites have exhibited an
impressive array of biological properties ranging from antimicrobial to insecticidal activities …

[HTML][HTML] Marine sponge aquaculture towards drug development: An ongoing history of technical, ecological, chemical considerations and challenges

M Maslin, N Gaertner-Mazouni, C Debitus, N Joy… - Aquaculture …, 2021 - Elsevier
Marine sponges have a long history of farming, starting with bath sponges over 5000 years
ago in the Mediterranean. Many species have since been found appropriate for distinct …

Advances in solution-and solid-phase synthesis toward the generation of natural product-like libraries

JP Nandy, M Prakesch, S Khadem, PT Reddy… - Chemical …, 2009 - ACS Publications
There is a growing interest in the use of small molecules as chemical probes in parallel to
classical genomic tools (gene expression, gene profiling, gene knockouts, and siRNA-based …

Citrinadin A, a Novel Pentacyclic Alkaloid from Marine-Derived Fungus Penicillium citrinum

M Tsuda, Y Kasai, K Komatsu, T Sone, M Tanaka… - Organic …, 2004 - ACS Publications
A novel pentacyclic alkaloid, citrinadin A (1), was isolated from the cultured broth of the
fungus Penicillium citrinum, which was separated from a marine red alga, and the structure …