Kinase inhibitors of marine origin
The ocean occupies three-fourths of the Earth's surface and hosts approximately 80% of all
living species. In fact, some areas of the sea such as coral reefs possess a biodiversity …
living species. In fact, some areas of the sea such as coral reefs possess a biodiversity …
A renaissance in marine pharmacology: from preclinical curiosity to clinical reality
KB Glaser, AMS Mayer - Biochemical pharmacology, 2009 - Elsevier
Marine pharmacology, the pharmacology of marine natural products, has been for some
time more associated with marine natural products chemistry rather than mainstay …
time more associated with marine natural products chemistry rather than mainstay …
Discorhabdins and pyrroloiminoquinone-related alkaloids
JF Hu, H Fan, J Xiong, SB Wu - Chemical reviews, 2011 - ACS Publications
Alkaloids, such as lamellarins1 and manzamines, 2 with complex structures and promising
biological activities produced by marine plants, invertebrates and microbes have greatly …
biological activities produced by marine plants, invertebrates and microbes have greatly …
Merging the potential of microbial genetics with biological and chemical diversity: an even brighter future for marine natural product drug discovery
Covering: 1999–2003Marine invertebrates and a growing number of marine bacteria are the
sources of novel, bioactive secondary metabolites. Structurally, many of these compounds …
sources of novel, bioactive secondary metabolites. Structurally, many of these compounds …
Culturable Actinobacteria from the Marine Sponge Hymeniacidon perleve: Isolation and Phylogenetic Diversity by 16S rRNA gene-RFLP Analysis
A total of 106 actinobacteria associated with the marine sponge Hymeniacidon perleve
collected from the Yellow Sea, China were isolated using eight different media. The number …
collected from the Yellow Sea, China were isolated using eight different media. The number …
Antimicrobial peptides from marine proteobacteria
After years of inadequate use and the emergence of multidrug resistant (MDR) strains, the
efficiency of “classical” antibiotics has decreased significantly. New drugs to fight MDR …
efficiency of “classical” antibiotics has decreased significantly. New drugs to fight MDR …
Volatile halogenated metabolites from marine red algae
M Kladi, C Vagias, V Roussis - Phytochemistry Reviews, 2004 - Springer
A significant number of halogenated low molecular weight metabolites have exhibited an
impressive array of biological properties ranging from antimicrobial to insecticidal activities …
impressive array of biological properties ranging from antimicrobial to insecticidal activities …
[HTML][HTML] Marine sponge aquaculture towards drug development: An ongoing history of technical, ecological, chemical considerations and challenges
M Maslin, N Gaertner-Mazouni, C Debitus, N Joy… - Aquaculture …, 2021 - Elsevier
Marine sponges have a long history of farming, starting with bath sponges over 5000 years
ago in the Mediterranean. Many species have since been found appropriate for distinct …
ago in the Mediterranean. Many species have since been found appropriate for distinct …
Advances in solution-and solid-phase synthesis toward the generation of natural product-like libraries
There is a growing interest in the use of small molecules as chemical probes in parallel to
classical genomic tools (gene expression, gene profiling, gene knockouts, and siRNA-based …
classical genomic tools (gene expression, gene profiling, gene knockouts, and siRNA-based …
Citrinadin A, a Novel Pentacyclic Alkaloid from Marine-Derived Fungus Penicillium citrinum
M Tsuda, Y Kasai, K Komatsu, T Sone, M Tanaka… - Organic …, 2004 - ACS Publications
A novel pentacyclic alkaloid, citrinadin A (1), was isolated from the cultured broth of the
fungus Penicillium citrinum, which was separated from a marine red alga, and the structure …
fungus Penicillium citrinum, which was separated from a marine red alga, and the structure …