Prolactinomas account for approximately 40% of all pituitary adenomas and are an
important cause of hypogonadism and infertility. The ultimate goal of therapy for …

I. The Problem of the Large Pituitary Tumor P ATIENTS with large pituitary tumors may
present with a variety of problems related to space occupation or endocrine dysfunction. The …

Prolactinomas in women commonly present as small intrasellar tumors, but are usually
much larger in men. This discrepancy has generally been attributed to differences in the …

Giant prolactinomas are rare tumours, representing only 2–3% of all prolactin (PRL)-
secreting tumours and raising special diagnostic and therapeutic challenges. Based on …

Giant pituitary adenomas comprise about 6–10% of all pituitary tumors. They are mostly
clinically non-functioning adenomas and occur predominantly in males. The presenting …

Background Giant prolactinomas are an unusual subset of macroprolactinomas and are
more commonly found in men. The goal of this review is to propose a giant prolactinoma …

Summary objective The term 'giant prolactinoma'can be used for tumours larger than 4 cm in
diameter and/or with massive extrasellar extension. Cabergoline (CAB), a long‐lasting …

Objective To review our experience with cabergoline, a D2-selective dopamine agonist, for
the treatment of giant prolactinomas. Design A retrospective case series; descriptive …

Pituitary tumors are mostly benign lesions, although 5–35% are locally invasive. A small
number exhibit a more aggressive course, infiltrating dura, bone and sinuses, and are …

Studies of DNA ploidy offer little diagnostic assistance and are of no prognostic significance
in predicting invasiveness of pituitary tumours [3, 18]; however, proliferative indices have …