Suppression of apoptosis in vascular endothelial cell, the promising way for natural medicines to treat atherosclerosis

H Duan, Q Zhang, J Liu, R Li, D Wang, W Peng… - Pharmacological …, 2021 - Elsevier
Atherosclerosis, a chronic multifactorial disease, is closely related to the development of
cardiovascular diseases and is one of the predominant causes of death worldwide. Normal …

[HTML][HTML] Berberine in cardiovascular and metabolic diseases: from mechanisms to therapeutics

X Feng, A Sureda, S Jafari, Z Memariani, D Tewari… - Theranostics, 2019 - ncbi.nlm.nih.gov
Cardiovascular and metabolic diseases (CVMD) are the leading causes of death worldwide,
underscoring the urgent necessity to develop new pharmacotherapies. Berberine (BBR) is …

Salvia miltiorrhizaBurge (Danshen): a golden herbal medicine in cardiovascular therapeutics

Z Li, S Xu, P Liu - Acta Pharmacologica Sinica, 2018 - nature.com
Abstract Salvia miltiorrhiza Burge (Danshen) is an eminent medicinal herb that possesses
broad cardiovascular and cerebrovascular protective actions and has been used in Asian …

Salvia miltiorrhiza in Treating Cardiovascular Diseases: A Review on Its Pharmacological and Clinical Applications

J Ren, L Fu, SH Nile, J Zhang, G Kai - Frontiers in pharmacology, 2019 - frontiersin.org
Bioactive chemical constitutes from the root of Salvia miltiorrhiza classified in two major
groups, viz., liposoluble tanshinones and water-soluble phenolics. Tanshinone IIA is a major …

ATP-citrate lyase (ACLY) in lipid metabolism and atherosclerosis: an updated review

X Feng, L Zhang, S Xu, A Shen - Progress in lipid research, 2020 - Elsevier
ATP citrate lyase (ACLY) is an important enzyme linking carbohydrate to lipid metabolism by
generating acetyl-CoA from citrate for fatty acid and cholesterol biosynthesis. Mendelian …

Therapeutic potential of polyphenols in cardiovascular diseases: Regulation of mTOR signaling pathway

A Sanches-Silva, L Testai, SF Nabavi, M Battino… - Pharmacological …, 2020 - Elsevier
Cardiovascular diseases comprise of non-communicable disorders that involve the heart
and/or blood vessels and have become the leading cause of death worldwide with …

Targeting foam cell formation in atherosclerosis: therapeutic potential of natural products

D Wang, Y Yang, Y Lei, NT Tzvetkov, X Liu… - Pharmacological …, 2019 - ASPET
Foam cell formation and further accumulation in the subendothelial space of the vascular
wall is a hallmark of atherosclerotic lesions. Targeting foam cell formation in the …

Rutaecarpine: a promising cardiovascular protective alkaloid from Evodia rutaecarpa (Wu Zhu Yu)

K Tian, J Li, S Xu - Pharmacological Research, 2019 - Elsevier
Rutaecarpine is a bioactive alkaloid isolated from Evodia rutaecarpa (Wu Zhu Yu, Family:
Rutaceae), a versatile medicinal herb which is clinically used to treat headache, abdominal …

Ethnopharmacology, phytochemistry, and pharmacology of Chinese Salvia species: A review

J Xu, K Wei, G Zhang, L Lei, D Yang, W Wang… - Journal of …, 2018 - Elsevier
Abstract Ethnopharmacological relevance The genus Salvia is one of the largest genera of
the Lamiaceae family. In China, about 40 Salvia species have been used as medicinal …

CD36 in atherosclerosis: pathophysiological mechanisms and therapeutic implications

K Tian, Y Xu, A Sahebkar, S Xu - Current atherosclerosis reports, 2020 - Springer
Abstract Purpose of Review Atherosclerosis is a chronic disease characterized by lipid
retention and inflammation in the artery wall. The retention and oxidation of low-density …