[HTML][HTML] Prevalence of polypharmacy and potentially inappropriate medications use in elderly Chinese patients: a systematic review and meta-analysis

F Tian, Z Chen, J Wu - Frontiers in Pharmacology, 2022 - frontiersin.org
Objectives: Polypharmacy and potentially inappropriate medication (PIM) use among elderly
Chinese patients have not yet been investigated by systematic review and meta-analysis …

[HTML][HTML] Global prevalence of polypharmacy and potentially inappropriate medication in older patients with dementia: a systematic review and meta-analysis

M Zhao, Z Chen, T Xu, P Fan, F Tian - Frontiers in Pharmacology, 2023 - frontiersin.org
Background: Older patients with dementia always need multiple drugs due to comorbidities
and cognitive impairment, further complicating drug treatment and increasing the risk of …

Optimising prescribing in older adults with multimorbidity and polypharmacy in primary care (OPTICA): cluster randomised clinical trial

KT Jungo, AK Ansorg, C Floriani, Z Rozsnyai… - bmj, 2023 - bmj.com
Objective To study the effects of a primary care medication review intervention centred
around an electronic clinical decision support system (eCDSS) on appropriateness of …

Polypharmacy and deprescribing: challenging the old and embracing the new

LK O'Donnell, K Ibrahim - BMC geriatrics, 2022 - Springer
People are living longer, and the World Health Organisation predicts that by 2050, 22% of
the world's population will be aged 60 years or older [1]. A common consequence of ageing …

A systematic review of randomised-controlled trials on deprescribing outcomes in older adults with polypharmacy

H Omuya, C Nickel, P Wilson… - International Journal of …, 2023 - academic.oup.com
Background Mixed findings about deprescribing impact have emerged from varied study
designs, interventions, outcome measures and targeting sub-categories of medications or …

European Respiratory Society statement on frailty in adults with chronic lung disease

CR Osadnik, LJ Brighton, C Burtin… - European …, 2023 - Eur Respiratory Soc
Frailty is a complex, multidimensional syndrome characterised by a loss of physiological
reserves that increases a person9s susceptibility to adverse health outcomes. Most …

Implementation considerations of deprescribing interventions: a scoping review

J Wang, JY Shen, Y Conwell… - Journal of internal …, 2024 - Wiley Online Library
Over half of older adults experience polypharmacy, including medications that may be
inappropriate or unnecessary. Deprescribing, which is the process of discontinuing or …

Deprescribing to optimise health outcomes for frail older people: a double-blind placebo-controlled randomised controlled trial—outcomes of the Opti-med study

C Etherton-Beer, A Page, V Naganathan… - Age and …, 2023 - academic.oup.com
Background potentially harmful polypharmacy is very common in older people living in aged
care facilities. To date, there have been no double-blind randomised controlled studies of …

[HTML][HTML] The anticholinergic burden: from research to practice

SN Hilmer, D Gnjidic - Australian Prescriber, 2022 - ncbi.nlm.nih.gov
The anticholinergic burden: from research to practice - PMC Back to Top Skip to main content
NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main …

Barriers and enablers to deprescribing in long-term care facilities: a 'best-fit'framework synthesis of the qualitative evidence

CH Heinrich, E Hurley, S McCarthy, S McHugh… - Age and …, 2022 - academic.oup.com
Introduction older adults are at risk of adverse outcomes due to a high prevalence of
polypharmacy and potentially inappropriate medications (PIMs). Deprescribing interventions …