Antibiotics have transformed modern medicine. They are essential for treating infectious
diseases and enable vital therapies and procedures. However, despite this success, their …

The ribosome is a multi-unit complex that translates mRNA into protein. Ribosome
biogenesis is the process that generates ribosomes and plays an essential role in cell …

The discovery of novel structural classes of antibiotics is urgently needed to address the
ongoing antibiotic resistance crisis,,,,,,,–. Deep learning approaches have aided in exploring …

The ribosome is a major target for clinically used antibiotics, but multidrug resistant
pathogenic bacteria are making our current arsenal of antimicrobials obsolete. Here we …

The widespread use of antibiotics has made multidrug-resistant bacteria (MDRB) one of the
greatest threats toward global health. Current conventional microbial detection methods are …

The pre-designable structure and unique architectures of covalent organic frameworks
(COFs) render them attractive as active and porous medium for water crisis. However, the …

Bacterial drug resistance is rapidly developing as one of the greatest threats to human
health. Bacteria will adopt corresponding strategies to crack the inhibitory effect of antibiotics …

The alarming rise in superbugs that are resistant to drugs of last resort, including
vancomycin-resistant enterococci and staphylococci, has become a significant global health …

Antimicrobial resistance is an exigent public health concern owing to the emergence of
novel strains of human resistant pathogens and the concurrent rise in multi-drug resistance …

The quaternization of compounds has emerged as a promising molecular design strategy for
the development of antibiotics. Herein, we report the design, synthesis, antibacterial …