ABSTRACT TACC3 is the most oncogenic member of the transforming acidic coiled-coil
domain-containing protein (TACC) family. It is one of the major recruitment factors of distinct …

The FGFR signaling pathway is integral to cellular activities, including proliferation,
differentiation, and survival. Dysregulation of this pathway is implicated in numerous human …

Tobacco smoking is the most important risk factor for bladder cancer. Previous studies have
identified the N‐acetyltransferase (NAT2) gene in association with bladder cancer risk. The …

Abstract FGFR3 and PIK3CA are among the most frequently mutated genes in bladder
tumors. We hypothesized that recurrent mutations in these genes might be caused by …

Background Bladder cancer (BLCA) research in Koreans is still lacking, especially in
focusing on the prediction of BLCA. The current study aimed to discover metabolic …

Objectives Absolute risk models estimate an individual's future disease risk over a specified
time interval. Applications utilizing server-side risk tooling, the R-based iCARE (R-iCARE), to …

Genomic studies of inherited and acquired variation are changing the landscape of our
understanding of the causes of urologic cancers and providing important translational …

Tobacco carcinogens metabolism-related genes (TCMGs) could generate reactive
metabolites of tobacco carcinogens, which subsequently contributed to multiple diseases …

Bladder cancer (BC) has been associated with genetic susceptibility. Single peptide
polymorphisms (SNPs) can modulate BC susceptibility. A literature search was performed …

Abstract Human N-acetyltransferase 2 (NAT2) is subject to genetic polymorphism in human
populations. In addition to the reference NAT2* 4 allele, two genetic variant alleles (NAT2 …