[HTML][HTML] Modeling Alzheimer's disease with iPSC-derived brain cells
Alzheimer's disease is a devastating neurodegenerative disorder with no cure. Countless
promising therapeutics have shown efficacy in rodent Alzheimer's disease models yet failed …
promising therapeutics have shown efficacy in rodent Alzheimer's disease models yet failed …
Current and future treatments for Alzheimer's disease
KG Yiannopoulou… - Therapeutic advances in …, 2013 - journals.sagepub.com
Alzheimer's dementia (AD) is increasingly being recognized as one of the most important
medical and social problems in older people in industrialized and non-industrialized …
medical and social problems in older people in industrialized and non-industrialized …
Increasing value and reducing waste in research design, conduct, and analysis
Correctable weaknesses in the design, conduct, and analysis of biomedical and public
health research studies can produce misleading results and waste valuable resources …
health research studies can produce misleading results and waste valuable resources …
Screening for cognitive impairment in older adults: a systematic review for the US Preventive Services Task Force
JS Lin, E O'Connor, RC Rossom… - Annals of internal …, 2013 - acpjournals.org
This article has been corrected. The original version (PDF) is appended to this article as a
supplement. Background: Earlier identification of cognitive impairment may reduce patient …
supplement. Background: Earlier identification of cognitive impairment may reduce patient …
Dementia in Down's syndrome
C Ballard, W Mobley, J Hardy, G Williams… - The Lancet …, 2016 - thelancet.com
Down's syndrome is the most common genetic cause of learning difficulties, and individuals
with this condition represent the largest group of people with dementia under the age of 50 …
with this condition represent the largest group of people with dementia under the age of 50 …
Omega‐3 fatty acids for the treatment of dementia
M Burckhardt, M Herke, T Wustmann… - Cochrane Database …, 2016 - cochranelibrary.com
Background Omega‐3 polyunsaturated fatty acids (omega‐3 PUFAs) from fish and plant
sources are commonly considered as a promising non‐medical alternative to improve brain …
sources are commonly considered as a promising non‐medical alternative to improve brain …
Inflammation and Alzheimer's disease
YJ Lee, SB Han, SY Nam, KW Oh, JT Hong - Archives of pharmacal …, 2010 - Springer
Alzheimer's disease (AD) is the most common form of dementia. It is characterized by
extracellular deposition of a specific protein, beta-amyloid peptide fibrils, and is …
extracellular deposition of a specific protein, beta-amyloid peptide fibrils, and is …
Machine learning-based virtual screening and its applications to Alzheimer's drug discovery: a review
KA Carpenter, X Huang - Current pharmaceutical design, 2018 - ingentaconnect.com
Background: Virtual Screening (VS) has emerged as an important tool in the drug
development process, as it conducts efficient in silico searches over millions of compounds …
development process, as it conducts efficient in silico searches over millions of compounds …
[HTML][HTML] Drugs for Alzheimer's disease: are they effective?
DA Casey, D Antimisiaris, J O'Brien - Pharmacy and Therapeutics, 2010 - ncbi.nlm.nih.gov
Alzheimer's disease (AD), a devastating neurodegenerative disorder, is the leading cause of
dementia in the US and in other developed countries. Patients experience progressive …
dementia in the US and in other developed countries. Patients experience progressive …
Adverse drug reactions of acetylcholinesterase inhibitors in older people living with dementia: a comprehensive literature review
S Ruangritchankul, P Chantharit… - … and clinical risk …, 2021 - Taylor & Francis
The rising of global geriatric population has contributed to increased prevalence of
dementia. Dementia is a neurodegenerative disease, which is characterized by progressive …
dementia. Dementia is a neurodegenerative disease, which is characterized by progressive …