Heart failure (HF) describes a heterogenous complex spectrum of pathological conditions
that results in structural and functional remodeling leading to subsequent impairment of …

Preclinical large animal models of heart failure (HF) play a critical and expanding role in
translating basic science findings to the development and clinical approval of novel …

It is necessary to understand the morphology of the vagus nerve (VN) to design and deliver
effective and selective vagus nerve stimulation (VNS) because nerve morphology influences …

In the modern world, myocardial infarction is one of the most common cardiovascular
diseases, which are responsible for around 18 million deaths every year or almost 32% of all …

Large animal models of cardiac ischemia-reperfusion are critical for evaluation of the
efficacy of cardioprotective interventions prior to clinical translation. Nonetheless, current …

Background Strategies to improve various cardiovascular diseases by blocking cardiac
sympathetic ganglion have been increasingly available currently. Botulinum toxin type A …

Our understanding of the complex pathophysiology of Heart failure with preserved ejection
fraction (HFpEF) is limited by the lack of a robust in vivo model. Existing in-vivo models …

Mechanical LV unloading for acute myocardial infarction (MI) is a promising supportive
therapy to reperfusion. However, no data is available on exit strategy. We evaluated …

Myocardial infarction is the most common cause of heart failure, one of the most fatal non-
communicable diseases worldwide. The disease could potentially be treated if the dead …

Restoring ischaemic myocardial tissue perfusion is crucial for minimizing infarct size. Acute
mechanical left ventricular (LV) support has been suggested to improve infarct tissue …