Mitochondria and ischemia–reperfusion injury of the heart: fixing a hole
F Di Lisa, P Bernardi - Cardiovascular research, 2006 - academic.oup.com
Ischemia and post-ischemic reperfusion cause a wide array of functional and structural
alterations of mitochondria. Although mitochondrial impairment is recognized as pivotal in …
alterations of mitochondria. Although mitochondrial impairment is recognized as pivotal in …
Protection against myocardial ischemia-reperfusion injury in clinical practice
D Garcia-Dorado, A Rodríguez-Sinovas… - Revista Española de …, 2014 - Elsevier
Even when reperfusion therapy is applied as early as possible, survival and quality of life
are compromised in a considerable number of patients with ST-segment elevation acute …
are compromised in a considerable number of patients with ST-segment elevation acute …
cGMP-elevating compounds and ischemic conditioning provide cardioprotection against ischemia and reperfusion injury via cardiomyocyte-specific BK channels
S Frankenreiter, P Bednarczyk, A Kniess, NI Bork… - Circulation, 2017 - Am Heart Assoc
Background: The nitric oxide–sensitive guanylyl cyclase/cGMP-dependent protein kinase
type I signaling pathway can afford protection against the ischemia/reperfusion injury that …
type I signaling pathway can afford protection against the ischemia/reperfusion injury that …
Membrane receptor‐dependent N otch1/H es1 activation by melatonin protects against myocardial ischemia–reperfusion injury: in vivo and in vitro studies
L Yu, H Liang, Z Lu, G Zhao, M Zhai… - Journal of pineal …, 2015 - Wiley Online Library
Melatonin confers profound protective effect against myocardial ischemia–reperfusion injury
(MI/RI). Activation of N otch1/H airy and enhancer of split 1 (H es1) signaling also …
(MI/RI). Activation of N otch1/H airy and enhancer of split 1 (H es1) signaling also …
AdipoRon, the first orally active adiponectin receptor activator, attenuates postischemic myocardial apoptosis through both AMPK-mediated and AMPK-independent …
Adiponectin (APN) is a cardioprotective molecule. Its reduction in diabetes exacerbates
myocardial ischemia/reperfusion (MI/R) injury. Although APN administration in animals …
myocardial ischemia/reperfusion (MI/R) injury. Although APN administration in animals …
Chronic treatment with rosuvastatin modulates nitric oxide synthase expression and reduces ischemia–reperfusion injury in rat hearts
P Di Napoli, AA Taccardi, A Grilli… - Cardiovascular …, 2005 - academic.oup.com
Objective: Due to reported modulatory effects of statins on nitric oxide synthase (NOS)
expression, we tested the hypothesis of protective effects of in vivo chronic treatment with …
expression, we tested the hypothesis of protective effects of in vivo chronic treatment with …
The effects of propofol on neutrophil function, lipid peroxidation and inflammatory response during elective coronary artery bypass grafting in patients with impaired …
TB Corcoran, A Engel, H Sakamoto… - BJA: British Journal …, 2006 - academic.oup.com
Background. Coronary artery bypass grafting (CABG) with cardiopulmonary bypass elicits a
potent reperfusion injury and inflammatory response, more intense in patients with impaired …
potent reperfusion injury and inflammatory response, more intense in patients with impaired …
The role of natural IgM in myocardial ischemia–reperfusion injury
M Zhang, LH Michael, SA Grosjean, RA Kelly… - Journal of molecular and …, 2006 - Elsevier
Myocardial ischemia–reperfusion injury represents a combination of factors, namely the
intrinsic cellular response to ischemia and the extrinsic acute inflammatory response …
intrinsic cellular response to ischemia and the extrinsic acute inflammatory response …
Fasudil protects the heart against ischemia-reperfusion injury by attenuating endoplasmic reticulum stress and modulating SERCA activity: the differential role for PI3K …
Y Li, W Zhu, J Tao, P Xin, M Liu, J Li, M Wei - PloS one, 2012 - journals.plos.org
Disordered calcium homeostasis can lead to endoplasmic reticulum (ER) stress. Our
previous data showed that time course activation of ER stress contributes to time-related …
previous data showed that time course activation of ER stress contributes to time-related …
Cardiac muscle membrane stabilization in myocardial reperfusion injury
The phospholipid bilayer membrane that surrounds each cell in the body represents the first
and last line of defense for preserving overall cell viability. In several forms of cardiac and …
and last line of defense for preserving overall cell viability. In several forms of cardiac and …