Lipids and Lipid Metabolism in Cellular Senescence: Emerging Targets for Age-Related Diseases
Q Zeng, YZ Gong, N Zhu, YN Shi, CJ Zhang… - Ageing Research …, 2024 - Elsevier
Cellular senescence is a kind of cellular state triggered by endogenous or exogenous
stimuli, which is mainly characterized by stable cell cycle arrest and complex senescence …
stimuli, which is mainly characterized by stable cell cycle arrest and complex senescence …
Immunosenescence and macrophages: from basics to therapeutics
H Zhu, F Shen, T Liao, H Qian, Y Liu - The International Journal of …, 2023 - Elsevier
Ageing decreases the function of the immune system and increases susceptibility to some
chronic, infectious, and autoimmune diseases. Senescence cells, which produce …
chronic, infectious, and autoimmune diseases. Senescence cells, which produce …
Subcellular targeting strategies for protein and peptide delivery
H Su, G Rong, L Li, Y Cheng - Advanced Drug Delivery Reviews, 2024 - Elsevier
Cytosolic delivery of proteins and peptides provides opportunities for effective disease
treatment, as they can specifically modulate intracellular processes. However, most of …
treatment, as they can specifically modulate intracellular processes. However, most of …
From cells to subcellular organelles: Next-generation cancer therapy based on peptide self-assembly
Due to the editability, functionality, and excellent biocompatibility of peptides, in situ self-
assembly of peptides in cells is a powerful strategy for biomedical applications. Subcellular …
assembly of peptides in cells is a powerful strategy for biomedical applications. Subcellular …
Senolytic Therapy Enabled by Senescent Cell‐Sensitive Biomimetic Melanin Nano‐senolytics
H Zhang, X Xu, X Shou, W Liao, C Jin… - Advanced …, 2024 - Wiley Online Library
Cellular senescence is a significant risk factor for aging and age‐related diseases (ARD).
The canonical senolytics Dasatinib and Quercetin (DQ) have shown promise in clearing …
The canonical senolytics Dasatinib and Quercetin (DQ) have shown promise in clearing …
[HTML][HTML] Targeting metabolism to influence cellular senescence a promising anti-cancer therapeutic strategy
Z Wang, J Gao, C Xu - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Metabolic disorders are considered the hallmarks of cancer and metabolic reprogramming is
emerging as a new strategy for cancer treatment. Exogenous and endogenous stressors can …
emerging as a new strategy for cancer treatment. Exogenous and endogenous stressors can …
Penetrating efficiency of supramolecular hydrogel eye drops: Electrostatic interaction surpasses ligand-receptor interaction
Z Ren, S Li, X Liu, G Lv, L Chen, J Wang, X Li… - Chinese Chemical …, 2024 - Elsevier
The low drug bioavailability of eye drops challenges the therapy of ocular disorders with
high efficacy. One of solutions is to extend the corneal retention and enhance the …
high efficacy. One of solutions is to extend the corneal retention and enhance the …
Discovery of a self-assembling small molecule that sequesters RNA-binding proteins
H Kim, C Cui, K Toh, G Ado, T Ogawa, Y Zhang… - Chinese Chemical …, 2024 - Elsevier
Biomolecular condensates, also known as membraneless organelles, play a crucial role in
cellular organization by concentrating or sequestering biomolecules. Despite their …
cellular organization by concentrating or sequestering biomolecules. Despite their …
Intracellular Chemical Reaction‐Induced Self‐Assembly for the Construction of Artificial Architecture and Its Functions
Intracellular assemblies play vital roles in maintaining cellular functions through structural
recognition‐mediated interactions. The introduction of artificial structures has garnered …
recognition‐mediated interactions. The introduction of artificial structures has garnered …
[PDF][PDF] Senolytic Therapy Enabled by Senescent Cell-Sensitive Biomimetic Melanin Nano
H Zhang, X Xu, X Shou, W Liao, C Jin, C Chen… - bookcafe.yuntsg.com
1. Introduction 21922659, ja, Downloaded from https://onlinelibrary. wiley. com/doi/10.1002/
adhm. 202401085 by Shanghai Jiaotong University, Wiley Online Library on [29/05/2024] …
adhm. 202401085 by Shanghai Jiaotong University, Wiley Online Library on [29/05/2024] …