During the last five years, there has been a significantly increasing interest in adult adipose
stem cells (ASCs) as a suitable tool for translational medicine applications. The abundant …

A major event in embryonic development is the rearrangement of epigenetic information as
the somatic genome is reprogrammed for a new round of organismal development …

Cell reprogramming is a revolutionized biotechnology that offers a powerful tool to engineer
cell fate and function for regenerative medicine, disease modeling, drug discovery, and …

Somatic cells can be reprogrammed into induced pluripotent stem cells (iPSCs) through
epigenetic manipulation. While the essential role of miRNA in reprogramming and …

The speed of reprogramming technologies evolution is rising dramatically in modern
science. Both the scientific community and health workers depend on such developments …

Embryonic stem cells (ESCs) maintain pluripotency through unique epigenetic states. When
ESCs commit to a specific lineage, epigenetic changes in histones and DNA accompany the …

In this review, we described different factors that modulate pluripotency in stem cells, in
particular we aimed at following the steps of two large families of miRNAs: the miR-200 …

Background: DNA methylation plays an important role in the reprogramming process.
Understanding the underlying molecular mechanism of reprogramming is crucial for …

Epigenetic enzymes regulate higher-order chromatin architecture and cell-type specific
gene expression. The ATPase BRG1 and the SWI/SNF chromatin remodeling complex are …

Abstract Background Long non-coding RNAs (lncRNAs), a type of epigenetic regulator, are
thought to play important roles in embryonic development in mice, and several …