During aortic surgery, interruption of spinal cord blood flow might cause spinal cord
ischemia‐reperfusion injury (IRI). The incidence of spinal cord IRI after aortic surgery is up to …

From the Departments of* Anesthesiology, and† Surgery, University of Wisconsin School of
Medicine and Public Health, Madison WI. Address reprint requests to. Martha M. Wynn, MD …

Background Spinal cord ischemia-reperfusion (I/R) involves two-phase injury, including an
initial acute ischemic insult and subsequent inflammatory reperfusion injury, resulting in …

Objectives Curcumin is a molecule found in turmeric root that possesses anti-inflammatory
and antioxidant properties and has been widely used to treat neurodegenerative diseases …

Spinal cord ischemia/reperfusion injury is a devastating medical disorder with poor
prognosis that is associated with several pathophysiological conditions. However, multiple …

OBJECTIVE:: Delayed paraplegia after operation on the thoracoabdominal aorta is
considered to be related to vulnerability of motor neurons to ischemia. Previous studies have …

The conservative nature of animal evolution makes animal models the ideal tool for learning
about human biology. The Handbook of Laboratory Animal Science, Second Edition: Animal …

An important component for successful translation of cell replacement‐based therapies into
clinical practice is the utilization of large animal models to conduct efficacy and/or safety cell …

The aim of this experimental study was to investigate the possible protective effects of
dantrolene on traumatic spinal cord injury (SCI). Twenty-four New Zealand rabbits were …

Objective: To develop a new, clinically relevant large animal model of pediatric spinal cord
injury (SCI) and compare the clinical and experimental features of pediatric SCI. Methods …