miRNAs as potential game-changers in retinoblastoma: Future clinical and medicinal uses

AS Doghish, HAM Moustafa, MS Elballal… - … -Research and Practice, 2023 - Elsevier
Retinoblastoma (RB) is a rare tumor in children, but it is the most common primitive
intraocular malignancy in childhood age, especially those below three years old. The RB …

[HTML][HTML] Multi-functionalized nanomaterials and nanoparticles for diagnosis and treatment of retinoblastoma

R Arshad, M Barani, A Rahdar, S Sargazi… - Biosensors, 2021 - mdpi.com
Retinoblastoma is a rare type of cancer, and its treatment, as well as diagnosis, is
challenging, owing to mutations in the tumor-suppressor genes and lack of targeted …

Genomic cfDNA analysis of aqueous humor in retinoblastoma predicts eye salvage: the surrogate tumor biopsy for retinoblastoma

JL Berry, L Xu, I Kooi, AL Murphree, RK Prabakar… - Molecular Cancer …, 2018 - AACR
Tumor-derived cell-free DNA (cfDNA) has biomarker potential; therefore, this study aimed to
identify cfDNA in the aqueous humor (AH) of retinoblastoma eyes and correlate somatic …

Bilayer hydrogel sheet‐type intraocular microrobot for drug delivery and magnetic nanoparticles retrieval

DI Kim, H Lee, SH Kwon, YJ Sung… - Advanced healthcare …, 2020 - Wiley Online Library
By virtue of minimum invasiveness and driving ability using a magnetic field, drug delivery
with the aid of a microrobot has an inherent potential for targeted treatment for the eye. The …

Potential of aqueous humor as a surrogate tumor biopsy for retinoblastoma

JL Berry, L Xu, AL Murphree, S Krishnan… - JAMA …, 2017 - jamanetwork.com
Importance Retinoblastoma (Rb) is one of the first tumors to have a known genetic etiology.
However, because biopsy of this tumor is contraindicated, it has not been possible to define …

Advances in biomaterials for the treatment of retinoblastoma

W Farhat, V Yeung, A Ross, F Kahale, N Boychev… - Biomaterials …, 2022 - pubs.rsc.org
Retinoblastoma is the most common primary intraocular malignancy in children. Although
traditional chemotherapy has shown some success in retinoblastoma management, there …

The role of long non-coding RNA AFAP1-AS1 in human malignant tumors

D Ji, X Zhong, X Jiang, K Leng, Y Xu, Z Li… - … -Research and Practice, 2018 - Elsevier
Abstract Objectives Long non-coding RNAs (lncRNAs) are a type Table of endogenous RNA
longer than 200 nucleotides in length, and this kind of RNAs lack or possess limited ability of …

Wedelolactone induces apoptosis and pyroptosis in retinoblastoma through promoting ROS generation

H Jiang, C Niu, Y Guo, Z Liu, Y Jiang - International Immunopharmacology, 2022 - Elsevier
Retinoblastoma is a most frequently occurring primary intraocular tumor in infancy and
children, highlighting the requirement to find and develop novel and more effective …

LncRNA AFAP1-AS1 is a prognostic biomarker and serves as oncogenic role in retinoblastoma

F Hao, Y Mou, L Zhang, S Wang, Y Yang - Bioscience reports, 2018 - portlandpress.com
The actin filament-associated protein 1 antisense RNA 1 (AFAP1-AS1) has been found to
serve as an oncogenic long noncoding RNA (lncRNA) in most types of human cancer. The …

Signaling pathways driving ocular malignancies and their targeting by bioactive phytochemicals

CR Croley, J Pumarol, BE Delgadillo, AC Cook… - Pharmacology & …, 2023 - Elsevier
Ocular cancers represent a rare pathology. The American Cancer Society estimates that
3,360 cases of ocular cancer occur annually in the United States. The major types of cancers …