Adipose tissue, colloquially known as" fat," is an extraordinarily flexible and heterogeneous
organ. While historically viewed as a passive site for energy storage, we now appreciate that …

Rather than serving as a mere onlooker, adipose tissue is a complex endocrine organ and
active participant in disease initiation and progression. Disruptions of biological processes …

Background The agony and economic strain of cancer and HIV/AIDS therapies severely
impact patients' psychological wellbeing. Meanwhile, sexual minorities experience …

Lipodystrophy syndromes are rare diseases originating from a generalized or partial loss of
adipose tissue. Adipose tissue dysfunction results from heterogeneous genetic or acquired …

Abstract Th17-polarized CD4+ effector T-cells together with their immunosuppressive
regulatory T-cell (Treg) counterparts, with transcriptional profiles governed by the lineage …

There is a growing body of evidence from both observational and randomised trials
implicating integrase inhibitors, particularly dolutegravir and bictegravir, with the …

Background We investigated the association between nonalcoholic fatty liver disease
(NAFLD) plus or minus a concurrent diagnosis of nonalcoholic steatohepatitis (NASH) and …

Drug-induced diabetes mellitus is a growing problem in clinical practice. New, potent
medications contribute to this problem in a population already at high risk of developing …

White adipose tissue (AT) contributes significantly to inflammation–especially in the context
of obesity. Several of AT's intrinsic features favor its key role in local and systemic …

Sexual issues tend to go unaddressed in human immunodeficiency virus (HIV)
management, although overt sexual dysfunctions are more prevalent in people living with …