Invasive fungal diseases are rare in individuals with intact immunity. This, together with the
fact that there are only a few species that account for most mycotic diseases, implies a …

The genus Cryptococcus contains two primary species complexes that are significant
opportunistic human fungal pathogens: C. neoformans and C. gattii. In humans …

Macrophages are key cellular components of innate immunity, acting as the first line of
defense against pathogens to modulate homeostatic and inflammatory responses. They …

Cryptococcus is an invasive fungus that seriously endangers human life and health, with a
complex and well-established immune-escaping mechanism that interferes with the function …

Cryptococcosis is a disease caused by the pathogenic fungi Cryptococcus neoformans and
Cryptococcus gattii, both environmental fungi that cause severe pneumonia and may even …

The dynamic and complex community of microbes that colonizes the intestines is composed
of bacteria, fungi, and viruses. At the mucosal surfaces, immunoglobulins play a key role in …

Cryptococcosis is an opportunistic disease caused by the fungus Cryptococcus neoformans
and Cryptococcus gattii. It starts as a pulmonary infection that can spread to other organs …

Cryptococcosis, a systemic mycosis that affects both the immunocompromised and
immunocompetent, is caused by the inhalation of dehydrated yeasts or fungal spores of …

The low efficacy and side effects associated with antifungal agents have highlighted the
importance of developing immunotherapeutic approaches to treat Cryptococcus gattii …

Upon encountering the host environment, fungal pathogens undergo morphogenic switches
to mediate immune evasion and dissemination. The Candida ablicans yeast-to-hyphal …