New dawn for atherosclerosis: Vascular endothelial cell senescence and death

LL Bu, HH Yuan, LL Xie, MH Guo, DF Liao… - International journal of …, 2023 - mdpi.com
Endothelial cells (ECs) form the inner linings of blood vessels, and are directly exposed to
endogenous hazard signals and metabolites in the circulatory system. The senescence and …

Mitochondria-targeted esculetin and metformin delay endothelial senescence by promoting fatty acid β-oxidation: Relevance in age-associated atherosclerosis

S Pulipaka, H Chempon, G Singuru, S Sahoo… - Mechanisms of Ageing …, 2024 - Elsevier
Impaired mitochondrial fatty acid β-oxidation (FAO) plays a role in the onset of several age-
associated diseases, including atherosclerosis. In the current work, we investigated the …

The Role of FoxO1 and Sex Differences in Response to a DNA-damaging Agent

CA Martone - 2024 - yorkspace.library.yorku.ca
Endothelial cell (EC) health can be disturbed in various diseases like aging, obesity,
atherosclerosis and type 2 diabetes. Previously, our lab showed that female ECs retain a …