Multidrug resistance (MDR) promotes tumor recurrence and metastasis and heavily reduces
anticancer efficiency, which has become a primary reason for the failure of clinical …

Tumour heterogeneity remains a major challenge in cancer therapy owing to the different
susceptibility of cells to chemotherapy within a solid tumour. Cancer stem-like cells (CSCs) …

All-Trans Retinoic Acid (ATRA) is the most active metabolite of vitamin A. It is critically
involved in the regulation of multiple processes, such as cell differentiation and apoptosis …

Cancer stem cells (CSCs) control tumor occurrence and development, chemotherapy
tolerance, and cancer recurrence and metastasis due to their characteristics of high …

Recurrence and metastasis have been recognized as a great challenge in cancer treatment.
Cancer stem cells (CSCs), as a small subset of cancer cells, are closely associated with …

A novel approach to treating cancer has been revealed to be effective cancer vaccination. It
has also been demonstrated that nucleic acid therapies such as mRNA and siRNA are very …

Postoperative recurrence of hepatocellular carcinoma (HCC) remains an important cause of
treatment failure. To mitigate the relapse of HCC, we have constructed an …

A coronavirus (CoV) commonly known as SARS-CoV-2 (severe acute respiratory syndrome
coronavirus 2) and causing COVID-19 (coronavirus disease of 2019) has become a …

Breast cancer is the most common malignant disease in women all over the world and its
chemotherapy outcome is restricted by multidrug resistance. Here, a nanostructure by …

Stem cells can be used to repair dysfunctional and injured (or cancerous) tissues by
delivering therapeutics. However, in comparison with other cells, it is harder to transfect …