Epigallocatechin-3-Gallate (EGCG): New therapeutic perspectives for neuroprotection, aging, and neuroinflammation for the modern age

A Payne, S Nahashon, E Taka, GM Adinew… - Biomolecules, 2022 - mdpi.com
Alzheimer's and Parkinson's diseases are the two most common forms of neurodegenerative
diseases. The exact etiology of these disorders is not well known; however, environmental …

Beneficial effects of natural flavonoids on neuroinflammation

Y Chen, F Peng, Z Xing, J Chen, C Peng… - Frontiers in …, 2022 - frontiersin.org
Neuroinflammation is the fundamental immune response against multiple factors in the
central nervous system and is characterized by the production of inflammatory mediators …

[HTML][HTML] Flavonoids: Their putative neurologic roles, epigenetic changes, and gut microbiota alterations in Parkinson's disease

Y Açar, D Ağagündüz, P De Cicco… - Biomedicine & …, 2023 - Elsevier
Abstract Parkinson's Disease (PD), a neurodegenerative disorder, is characterized by the
degeneration of progressive dopaminergic (DA) neurons in the substantia nigra region of …

Epigallocatechin-3-gallate: A phytochemical as a promising drug candidate for the treatment of Parkinson's disease

Y Wang, S Wu, Q Li, W Lang, W Li, X Jiang… - Frontiers in …, 2022 - frontiersin.org
Epigallocatechin 3-gallate (EGCG), an abundant polyphenolic component derived from
green tea extract, possesses versatile bioactivities that can combat many diseases. During …

Green tea catechins attenuate neurodegenerative diseases and cognitive deficits

O Afzal, MH Dalhat, ASA Altamimi, R Rasool… - Molecules, 2022 - mdpi.com
Neurodegenerative diseases exert an overwhelming socioeconomic burden all around the
globe. They are mainly characterized by modified protein accumulation that might trigger …

Green tea epigallocatechin-3-gallate (EGCG) targeting protein misfolding in drug discovery for neurodegenerative diseases

PB Gonçalves, ACR Sodero, Y Cordeiro - Biomolecules, 2021 - mdpi.com
The potential to treat neurodegenerative diseases (NDs) of the major bioactive compound of
green tea, epigallocatechin-3-gallate (EGCG), is well documented. Numerous findings now …

Natural phytochemicals as novel therapeutic strategies to prevent and treat Parkinson's disease: current knowledge and future perspectives

R Balakrishnan, S Azam, DY Cho… - Oxidative Medicine …, 2021 - Wiley Online Library
Parkinson's disease (PD) is the second‐most common neurodegenerative chronic disease
affecting both cognitive performance and motor functions in aged people. Yet despite the …

Neuroprotective Properties of Green Tea (Camellia sinensis) in Parkinson's Disease: A Review

DS Malar, MI Prasanth, JM Brimson, R Sharika… - Molecules, 2020 - mdpi.com
Neurodegenerative disease is a collective term given for the clinical condition, which results
in progressive degeneration of neurons and the loss of functions associated with the …

Potential role of natural polyphenols against protein aggregation toxicity: in vitro, in vivo, and clinical studies

G Henríquez, A Gomez, E Guerrero… - ACS Chemical …, 2020 - ACS Publications
One of the main features of neurodegenerative disorders such as Alzheimer's disease and
Parkinson's disease is the amyloidogenic behavior of disease-specific proteins including …

[HTML][HTML] Promising polyphenols in Parkinson's disease therapeutics

A Singh, P Tripathi, AK Yadawa, S Singh - Neurochemical Research, 2020 - Springer
Parkinson's disease (PD) is a slow progressive, second most common neurodegenerative
disease characterized by the loss of dopaminergic neurons from the nigrostriatal pathway. In …