Glomerular podocyte damage is considered to be one of the main mechanisms leading to
Diabetic nephropathy (DN). However, the relevant mechanism of podocyte injury is not yet …

Cardiovascular remodeling occurs in cardiomyocytes, collagen meshes, and vascular beds
in the progress of cardiac insufficiency caused by a variety of cardiac diseases such as …

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), the prime causes of
morbidity and mortality in critically ill patients, are usually treated by general supportive …

The Ca2+ release in microdomains formed by intercompartmental contacts, such as
mitochondria-associated endoplasmic reticulum membranes (MAMs), encodes a signal that …

Background Many clinical studies have shown a correlation between proton pump inhibitors
(PPIs) and osteoporosis or fractures. The purpose of this study was to establish a murine …

Previous studies revealed a cardioprotective potential of Panax notoginseng to relieve acute
myocardial infarction and focal cerebral ischemia‐reperfusion. However, whether P …

Muscone is the main active compound of Moschus. In this paper, the cardioprotective effect
of Muscone on acute myocardial ischemia (AMI) rats and its potential mechanisms were …

Background: Abnormal activation of endoplasmic reticulum (ER) stress sensors and their
downstream signalling pathways is a key regulator of tumour growth, tumour metastasis and …

Intervertebral disc degeneration (IDD) is a major cause of low back pain (LBP), but there is
still a lack of effective therapy. Multiple studies have reported that endoplasmic reticulum …

Cardiovascular disease (CVD), a leading cause of morbidity and mortality, is among the
most prevalent health problems worldwide and effective strategies for its prevention and …