With the rapid development of the global industrialization process, as an important energy
and strategic resource, petroleum is widely used in various fields. Meanwhile, the leakage of …

Cell metabolomics is a comprehensive analytical approach to study small biological
molecules involved in many fundamental intracellular functions, linking mechanistic …

The annotation of genomes from NGS platforms needs to be automated and fully integrated.
However, maintaining consistency and accuracy in genome annotation is a challenging …

One primary objective of synthetic biology is to improve the sustainability of chemical
manufacturing. Naturally occurring biological systems can utilize a variety of carbon sources …

Acinetobacter baylyi ADP1 is a non-pathogenic soil bacterium known for its metabolic
diversity and high natural transformation and recombination efficiency. For these features, A …

Background In all living organisms, DNA replication is exquisitely regulated in a wide range
of growth conditions to achieve timely and accurate genome duplication prior to cell division …

Experimental validation of enzyme function is crucial for genome interpretation, but it
remains challenging because it cannot be scaled up to accommodate the constant …

One goal of synthetic biology is to improve the efficiency and predictability of living cells by
removing extraneous genes from their genomes. We demonstrate improved methods for …

Staphylococcus aureus can cause a variety of severe disease patterns and can readily
acquire antibiotic resistance; however, the mechanisms by which this commensal becomes …

Aromatic compounds are the second most abundant class of organic compounds in nature
after carbohydrates and they derive mostly from the polymer lignin. Soluble plant-derived …