Prostate cancer and bone: the elective affinities

N Rucci, A Angelucci - BioMed research international, 2014 - Wiley Online Library
The onset of metastases dramatically changes the prognosis of prostate cancer patients,
determining increased morbidity and a drastic fall in survival expectancy. Bone is a common …

Peptide vaccines and peptidomimetics targeting HER and VEGF proteins may offer a potentially new paradigm in cancer immunotherapy

PTP Kaumaya, KC Foy - Future oncology, 2012 - Taylor & Francis
The ErbB family (HER-1, HER-2, HER-3 and HER-4) of receptor tyrosine kinases has been
the focus of cancer immunotherapeutic strategies while antiangiogenic therapies have …

[HTML][HTML] Molecular pathogenesis of bone metastases in breast cancer: Proven and emerging therapeutic targets

N Rucci, P Sanità, S Delle Monache… - World journal of …, 2014 - ncbi.nlm.nih.gov
Metastatic occurrence is the principal cause of death in breast cancer patients. The high
osteotropism makes breast cancer the most common primary tumor type associated with …

Differential effects of low‐and high‐dose GW2974, a dual epidermal growth factor receptor and HER2 kinase inhibitor, on glioblastoma multiforme invasion

L Wang, Q Liu, H Zhao, K Cui, L Yao… - Journal of …, 2013 - Wiley Online Library
Aberrant expression of epidermal growth factor receptor (EGFR; ErbB1) and HER2 (ErbB2)
tyrosine kinases frequently occurs in glioblastoma multiforme (GBM) patients and is …

Cancer multitarget pharmacology in prostate tumors: tyrosine kinase inhibitors and beyond

M Bologna, C Vicentini, P Muzi, G Pace… - Current medicinal …, 2011 - ingentaconnect.com
Tyrosine kinase inhibitors are currently one of the most important classes of cancer drugs,
essentially because many kinases and regulators are molecules related to frequently …

[PDF][PDF] Obtención de los dominios extracelulares del HER1 y el HER2 acoplados a etiqueta de histidina para su empleo como antígenos de una vacuna específica por …

DCBS Ramírez - 2024 - accesoabierto.uh.cu
La estrecha relación existente entre los receptores para el factor de crecimiento epidérmico
humanos HER1 y HER2 (del inglés,“human epidermal growth factor receptors 1-2”) y la …

ErbB receptors as prognostic and therapeutic drug targets in bone and soft tissue sarcomas

H Wang, Q Yang, Z Fu, D Zuo, Y Hua, Z Cai - Cancer Investigation, 2014 - Taylor & Francis
ErbB receptors have been intensely studied to understand their importance in cancer
biology and as therapeutic targets, and many ErbB inhibitors are now used in the clinical …

HER-1, HER-3 and IGF-1R compositions and uses thereof

PTP Kaumaya - US Patent 10,800,834, 2020 - Google Patents
Provided herein are HER-3, HER-1 and IGF-1R B cell epitopes, peptide mimics, chimeric
peptides and multivalent peptides. In some embodiments, the chimeric peptides include one …

HER-1, HER-3 and IGF-1R compositions and uses thereof

PTP Kaumaya - US Patent 10,221,230, 2019 - Google Patents
Provided herein are HER-3, HER-1 and IGF-1R B cell epitopes, peptide mimics, chimeric
peptides and multivalent peptides. In some embodiments, the chimeric peptides include one …

Nadia Rucci, Luca Ventura, and Anna Teti

L Ventura - Biotargets of Cancer in Current Clinical Practice, 2012 - books.google.com
The mammary gland is a specialized accessory gland of the skin. According to the
histological features, it can be classified as an exocrine, tubular-alveolar gland organized in …