Fiber types in mammalian skeletal muscles
S Schiaffino, C Reggiani - Physiological reviews, 2011 - journals.physiology.org
Mammalian skeletal muscle comprises different fiber types, whose identity is first established
during embryonic development by intrinsic myogenic control mechanisms and is later …
during embryonic development by intrinsic myogenic control mechanisms and is later …
Moving into the cell: single-molecule studies of molecular motors in complex environments
C Veigel, CF Schmidt - Nature Reviews Molecular Cell Biology, 2011 - nature.com
Much has been learned in the past decades about molecular force generation. Single-
molecule techniques, such as atomic force microscopy, single-molecule fluorescence …
molecule techniques, such as atomic force microscopy, single-molecule fluorescence …
[HTML][HTML] Multistep orthophosphate release tunes actomyosin energy transduction
L Moretto, M Ušaj, O Matusovsky, DE Rassier… - Nature …, 2022 - nature.com
Muscle contraction and a range of critical cellular functions rely on force-producing
interactions between myosin motors and actin filaments, powered by turnover of adenosine …
interactions between myosin motors and actin filaments, powered by turnover of adenosine …
[HTML][HTML] Skeletal muscle performance determined by modulation of number of myosin motors rather than motor force or stroke size
Skeletal muscle can bear a high load at constant length, or shorten rapidly when the load is
low. This force-velocity relationship is the primary determinant of muscle performance in …
low. This force-velocity relationship is the primary determinant of muscle performance in …
High Resolution Cryo-EM Structures of Actin-Bound Myosin States Reveal the Mechanism of Myosin Force Sensing
Myosin motors are able to dynamically adjust their power outputs in response to mechanical
loads, with different isoforms differing substantially in their force sensitivities. While it is …
loads, with different isoforms differing substantially in their force sensitivities. While it is …
Mechanics of actomyosin bonds in different nucleotide states are tuned to muscle contraction
B Guo, WH Guilford - … of the National Academy of Sciences, 2006 - National Acad Sciences
Muscle contraction and many other cell movements are driven by cyclic interactions
between actin filaments and the motor enzyme myosin. Conformational changes in the actin …
between actin filaments and the motor enzyme myosin. Conformational changes in the actin …
DNA damage response in adult stem cells: pathways and consequences
PK Mandal, C Blanpain, DJ Rossi - Nature Reviews Molecular Cell …, 2011 - nature.com
In contrast to postmitotic or short-lived somatic cells, tissue-specific stem cells must persist
and function throughout life to ensure tissue homeostasis and repair. The enormous …
and function throughout life to ensure tissue homeostasis and repair. The enormous …
[HTML][HTML] Interrogating biology with force: single molecule high-resolution measurements with optical tweezers
M Capitanio, FS Pavone - Biophysical journal, 2013 - cell.com
Single molecule force spectroscopy methods, such as optical and magnetic tweezers and
atomic force microscopy, have opened up the possibility to study biological processes …
atomic force microscopy, have opened up the possibility to study biological processes …
Nonlinear elasticity and an 8-nm working stroke of single myosin molecules in myofilaments
Using optical trapping and fluorescence imaging techniques, we measured the step size
and stiffness of single skeletal myosins interacting with actin filaments and arranged on …
and stiffness of single skeletal myosins interacting with actin filaments and arranged on …
Impact of sleep bruxism on masseter and temporalis muscles and bite force
Objectives: This study aimed to analyze the impact of sleep bruxism (SB) on
electromyography (EMG) activity and the thickness of the masseter and temporal and …
electromyography (EMG) activity and the thickness of the masseter and temporal and …