Mammalian skeletal muscle comprises different fiber types, whose identity is first established
during embryonic development by intrinsic myogenic control mechanisms and is later …

Much has been learned in the past decades about molecular force generation. Single-
molecule techniques, such as atomic force microscopy, single-molecule fluorescence …

Muscle contraction and a range of critical cellular functions rely on force-producing
interactions between myosin motors and actin filaments, powered by turnover of adenosine …

Skeletal muscle can bear a high load at constant length, or shorten rapidly when the load is
low. This force-velocity relationship is the primary determinant of muscle performance in …

Myosin motors are able to dynamically adjust their power outputs in response to mechanical
loads, with different isoforms differing substantially in their force sensitivities. While it is …

Muscle contraction and many other cell movements are driven by cyclic interactions
between actin filaments and the motor enzyme myosin. Conformational changes in the actin …

In contrast to postmitotic or short-lived somatic cells, tissue-specific stem cells must persist
and function throughout life to ensure tissue homeostasis and repair. The enormous …

Single molecule force spectroscopy methods, such as optical and magnetic tweezers and
atomic force microscopy, have opened up the possibility to study biological processes …

Using optical trapping and fluorescence imaging techniques, we measured the step size
and stiffness of single skeletal myosins interacting with actin filaments and arranged on …

Objectives: This study aimed to analyze the impact of sleep bruxism (SB) on
electromyography (EMG) activity and the thickness of the masseter and temporal and …