Changing epidemiology of invasive pneumococcal disease among older adults in the era of pediatric pneumococcal conjugate vaccine

CA Lexau, R Lynfield, R Danila, T Pilishvili, R Facklam… - Jama, 2005 - jamanetwork.com
ContextA conjugate vaccine targeting 7 pneumococcal serotypes was licensed for young
children in 2000. In contrast to the 23-valent polysaccharide vaccine used in adults, the 7 …

Prior pneumococcal vaccination is associated with reduced death, complications, and length of stay among hospitalized adults with community-acquired pneumonia

DN Fisman, E Abrutyn, KA Spaude… - Clinical infectious …, 2006 - academic.oup.com
Background. Vaccination with pneumococcal polysaccharide reduces the incidence of
bacteremic pneumococcal disease in adults. We investigated the impact of prior …

[HTML][HTML] Immune responses to pneumococcal vaccines in children and adults: rationale for age-specific vaccination

MAJ Westerink, HW Schroeder Jr, MH Nahm - Aging and disease, 2012 - ncbi.nlm.nih.gov
Streptococcus pneumoniae is a significant human pathogen and currently available
pneumococcal vaccines are designed to elicit anti-capsule antibodies. The 23-valent …

[HTML][HTML] Treatment and prevention of acute respiratory infections among Iranian hajj pilgrims: a 5-year follow up study and review of the literature

SM Razavi, SM Torabi, P Salamati - … of the Islamic Republic of Iran, 2014 - ncbi.nlm.nih.gov
Background Respiratory diseases/syndromes are the most common causes of referring to
physicians among pilgrims in Hajj. They lead to high morbidity, impose high costs on the …

Advances in pneumococcal vaccines: what are the advantages for the elderly?

A Vila-Córcoles - Drugs & aging, 2007 - Springer
Streptococcus pneumoniae causes considerable morbidity and mortality in the elderly.
There are three established approaches to pneumococcal vaccination: polysaccharide …

Th1 Cytokines Facilitate CD8-T-Cell-Mediated Early Resistance to Infection with Mycobacterium tuberculosis in Old Mice

B Vesosky, DK Flaherty, J Turner - Infection and immunity, 2006 - Am Soc Microbiol
Numerous immunological defects begin to emerge as an individual ages, the consequence
of which is heightened susceptibility to infectious diseases. Despite this decline in immune …

Immune response to pneumococcal polysaccharides 4 and 14 in elderly and young adults. I Antibody concentrations, avidity and functional activity

K Kolibab, SL Smithson, AK Shriner, S Khuder… - Immunity & …, 2005 - Springer
Streptococcus pneumoniae is a serious worldwide pathogen and the focus of numerous
vaccine development projects. Currently the most widely accepted surrogate marker for …

Immune response to pneumococcal polysaccharides 4 and 14 in elderly and young adults: analysis of the variable heavy chain repertoire

K Kolibab, SL Smithson, B Rabquer… - Infection and …, 2005 - Am Soc Microbiol
Streptococcus pneumoniae is a leading cause of morbidity and mortality in both developed
and developing countries. The current pneumococcal polysaccharide (PPS) vaccine is …

The impact and effectiveness of pneumococcal vaccination in Scotland for those aged 65 and over during winter 2003/2004

JD Mooney, A Weir, J McMenamin, LD Ritchie… - BMC infectious …, 2008 - Springer
Abstract Background For winter 2003/2004 in Scotland, it was recommended that all those
aged 65 and over be eligible to receive 23-valent polysaccharide pneumococcal vaccine …

Influence of asthma status on serotype-specific pneumococcal antibody levels

JA Jung, H Kita, R Dhillon, RM Jacobson… - Postgraduate …, 2010 - Taylor & Francis
Background: Asthma has been reported to be associated with an increased risk of invasive
pneumococcal disease (IPD). Objective: We compared serotype-specific antibody …