In this study, full-genome DNA microarrays based on the sequence of Staphylococcus
aureus N315 were used to compare the transcriptome of a clinical S. aureus strain with a …

Background Neisseria meningitidis is a human pathogen that can infect diverse sites within
the human host. The major diseases caused by N. meningitidis are responsible for death …

Cystic fibrosis (CF) is a fatal genetic disease characterized by chronic lung infections due to
aberrant mucus production and the inability to clear invading pathogens. The traditional …

We have characterized the master regulator of cysteine metabolism, CymR, in
Staphylococcus aureus. CymR repressed the transcription of genes involved in pathways …

Background Compared to other omics techniques, quantitative metabolomics is still at its
infancy. Complex sample preparation and analytical procedures render exact quantification …

Background Modeling of metabolic networks includes tasks such as network assembly,
network overview, calculation of metabolic fluxes and testing the robustness of the network …

Anaerobic Clostridium spp. is an important bioproduction microbial genus that can produce
solvents and utilize a broad spectrum of substrates including cellulose and syngas. Genome …

The normal and abnormal behavior of a living cell is governed by complex networks of
interacting biomolecules. Models of these networks allow us to make predictions about …

Flux balance analysis (FBA) is a computational method to analyze reconstructions of
biochemical networks. FBA requires the formulation of a biochemical network in a precise …

Chlorophyll is one of the most important pigments present in green plants and rice is one of
the major food crops consumed worldwide. We curated the existing genome scale metabolic …