Advances in dendritic cell targeting nano-delivery systems for induction of immune tolerance

G Lin, J Wang, YG Yang, Y Zhang… - Frontiers in Bioengineering …, 2023 - frontiersin.org
Dendritic cells (DCs) are the major specialized antigen-presenting cells (APCs), play a key
role in initiating the body's immune response, maintain the balance of immunity. DCs can …

Emerging strategies for nanomedicine in autoimmunity

AS Thatte, MM Billingsley, D Weissman… - Advanced Drug Delivery …, 2024 - Elsevier
Autoimmune disorders have risen to be among the most prevalent chronic diseases across
the globe, affecting approximately 5–7% of the population. As autoimmune diseases steadily …

Hsa-miR-21–5p reflects synovitis and tenosynovitis components of musculoskeletal ultrasonography Seven-joint scores in rheumatoid arthritis disease and predicts …

R Hammad, MA Eldosoky, C Lambert, U Sack… - … -Research and Practice, 2024 - Elsevier
Rheumatoid arthritis (RA) is characterized by progressive joint destruction with subsequent
serious disability. Objective biomarkers of RA course progression are lacking, which …

Rational engineering of islet tolerance via biomaterial-mediated immune modulation

N Klug, J Burke, E Scott - The Journal of Immunology, 2024 - journals.aai.org
Abstract Type 1 diabetes (T1D) onset is characterized by an autoimmune attack on β islet
cells within the pancreas, preventing the insulin secretion required to maintain glucose …

Advancing immunotherapy using biomaterials to control tissue, cellular, and molecular level immune signaling in skin

SA Shah, RS Oakes, CM Jewell - Advanced Drug Delivery Reviews, 2024 - Elsevier
Immunotherapies have been transformative in many areas, including cancer treatments,
allergies, and autoimmune diseases. However, significant challenges persist in extending …

Engineering metabolism to modulate immunity

SM Kapnick, CA Martin, CM Jewell - Advanced Drug Delivery Reviews, 2023 - Elsevier
Metabolic programming and reprogramming have emerged as pivotal mechanisms for
altering immune cell function. Thus, immunometabolism has become an attractive target …