Chronic kidney disease

K Kalantar-Zadeh, TH Jafar, D Nitsch, BL Neuen… - The lancet, 2021 - thelancet.com
Chronic kidney disease is a progressive disease with no cure and high morbidity and
mortality that occurs commonly in the general adult population, especially in people with …

[HTML][HTML] GLP-1 receptor agonists in the treatment of type 2 diabetes–state-of-the-art

MA Nauck, DR Quast, J Wefers, JJ Meier - Molecular metabolism, 2021 - Elsevier
Background GLP-1 receptor agonists (GLP-1 RAs) with exenatide bid first approved to treat
type 2 diabetes in 2005 have been further developed to yield effective compounds …

The Lancet Commission on diabetes: using data to transform diabetes care and patient lives

JCN Chan, LL Lim, NJ Wareham, JE Shaw, TJ Orchard… - The Lancet, 2020 - thelancet.com
Executive summary 2020 will go down in history as the year when the global community was
awakened to the fragility of human health and the interdependence of the ecosystem …

2019 update to: management of hyperglycemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European …

JB Buse, DJ Wexler, A Tsapas, P Rossing… - Diabetes …, 2020 - Am Diabetes Assoc
The American Diabetes Association and the European Association for the Study of Diabetes
have briefly updated their 2018 recommendations on management of hyperglycemia, based …

Durability of a primary care-led weight-management intervention for remission of type 2 diabetes: 2-year results of the DiRECT open-label, cluster-randomised trial

MEJ Lean, WS Leslie, AC Barnes… - The lancet Diabetes & …, 2019 - thelancet.com
Summary Background The DiRECT trial assessed remission of type 2 diabetes during a
primary care-led weight-management programme. At 1 year, 68 (46%) of 149 intervention …

Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus

M Foretz, B Guigas, B Viollet - Nature Reviews Endocrinology, 2019 - nature.com
Despite its position as the first-line drug for treatment of type 2 diabetes mellitus, the
mechanisms underlying the plasma glucose level-lowering effects of metformin (1, 1 …

American Association of Clinical Endocrinology clinical practice guideline: the use of advanced technology in the management of persons with diabetes mellitus

G Grunberger, J Sherr, M Allende, T Blevins, B Bode… - Endocrine practice, 2021 - Elsevier
Objective To provide evidence-based recommendations regarding the use of advanced
technology in the management of persons with diabetes mellitus to clinicians, diabetes-care …

Dipeptidyl peptidase 4 inhibitors in the treatment of type 2 diabetes mellitus

CF Deacon - Nature Reviews Endocrinology, 2020 - nature.com
Dipeptidyl peptidase 4 inhibitors (DPP4i) have been available for treating type 2 diabetes
mellitus since 2006. Although they are a diverse group, DPP4i are all small, orally available …

Machine learning based diabetes classification and prediction for healthcare applications

UM Butt, S Letchmunan, M Ali… - Journal of healthcare …, 2021 - Wiley Online Library
The remarkable advancements in biotechnology and public healthcare infrastructures have
led to a momentous production of critical and sensitive healthcare data. By applying …

Oral semaglutide versus subcutaneous liraglutide and placebo in type 2 diabetes (PIONEER 4): a randomised, double-blind, phase 3a trial

R Pratley, A Amod, ST Hoff, T Kadowaki, I Lingvay… - The Lancet, 2019 - thelancet.com
Summary Background Glucagon-like peptide-1 (GLP-1) receptor agonists are effective
treatments for type 2 diabetes, lowering glycated haemoglobin (HbA 1c) and weight, but are …