Digital health application integrating wearable data and behavioral patterns improves metabolic health

AD Zahedani, T McLaughlin, A Veluvali… - NPJ Digital …, 2023 - nature.com
The effectiveness of lifestyle interventions in reducing caloric intake and increasing physical
activity for preventing Type 2 Diabetes (T2D) has been previously demonstrated. The use of …

A carbohydrate-reduced high-protein diet improves HbA1c and liver fat content in weight stable participants with type 2 diabetes: a randomised controlled trial

MJ Skytte, A Samkani, AD Petersen, MN Thomsen… - Diabetologia, 2019 - Springer
Aims/hypothesis Dietary recommendations for treating type 2 diabetes are unclear but a
trend towards recommending a diet reduced in carbohydrate content is acknowledged. We …

Uses and limitations of the restricted mean survival time: illustrative examples from cardiovascular outcomes and mortality trials in type 2 diabetes

DE Kloecker, MJ Davies, K Khunti… - Annals of internal …, 2020 - acpjournals.org
The restricted mean survival time (RMST) has been advocated as an alternative or a
supplement to the hazard ratio for reporting the effect of an intervention in a randomized …

Cardiovascular effects of glucagon-like peptide 1 receptor agonists: from mechanistic studies in humans to clinical outcomes

VD Heuvelman, DH Van Raalte… - Cardiovascular …, 2020 - academic.oup.com
Type 2 diabetes mellitus (T2DM) is currently one of the most prevalent diseases, with as
many as 415 million patients worldwide. T2DM is characterized by elevated blood glucose …

DPP-4 inhibition and the path to clinical proof

B Ahrén - Frontiers in endocrinology, 2019 - frontiersin.org
In the 1990s it was discovered that the enzyme dipeptidyl peptidase-4 (DPP-4) inactivates
the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent …

Self-care is renouncement, routine, and control: The experience of adults with type 2 diabetes mellitus

M Luciani, L Montali, G Nicolo, D Fabrizi… - Clinical nursing …, 2021 - journals.sagepub.com
Type 2 Diabetes Mellitus can cause serious complications; it has a severe impact on the
quality of life and high costs. One of the key strategies to manage diabetes is self-care, a …

Protective effects of sodium-glucose transporter 2 inhibitors on atrial fibrillation and atrial flutter: a systematic review and meta-analysis of randomized placebo …

D Li, Y Liu, TH Hidru, X Yang, Y Wang… - Frontiers in …, 2021 - frontiersin.org
Background Hyperglycemia is associated with an increased risk of developing atrial
fibrillation (AF) and atrial flutter (AFL). Sodium-glucose transporter 2 inhibitors (SGLT2i) …

The effects of SGLT2 inhibitors on cardiovascular and renal outcomes in diabetic patients: a systematic review and meta-analysis

KB Lo, F Gul, P Ram, AY Kluger, KM Tecson… - Cardiorenal …, 2020 - karger.com
Background: Previous meta-analyses demonstrated the benefits of sodium-glucose
cotransporter 2 inhibitors (SGLT2i) primarily on patients with established atherosclerotic …

[HTML][HTML] Intensified multifactorial intervention in patients with type 2 diabetes mellitus

T Sasako, T Yamauchi, K Ueki - Diabetes & Metabolism …, 2023 - synapse.koreamed.org
In the management of diabetes mellitus, one of the most important goals is to prevent its
micro-and macrovascular complications, and to that end, multifactorial intervention is widely …

Reconsidering the role of glycaemic control in cardiovascular disease risk in type 2 diabetes: a 21st century assessment

VR Aroda, RH Eckel - Diabetes, Obesity and Metabolism, 2022 - Wiley Online Library
It is well known that the multiple factors contributing to the pathogenesis of type 2 diabetes
(T2D) confer an increased risk of developing cardiovascular disease (CVD). Although the …