[HTML][HTML] Modulation of the hypothalamic-pituitary-adrenal axis by early life stress exposure

M Van Bodegom, JR Homberg… - Frontiers in cellular …, 2017 - frontiersin.org
Exposure to stress during critical periods in development can have severe long-term
consequences, increasing overall risk on psychopathology. One of the key stress response …

Transgenerational epigenetic inheritance in mammals: how good is the evidence?

SD van Otterdijk, KB Michels - The FASEB Journal, 2016 - Wiley Online Library
Epigenetics plays an important role in orchestrating key biologic processes. Epigenetic
marks, including DNA methylation, histones, chromatin structure, and noncoding RNAs, are …

[HTML][HTML] Epigenetic inheritance: concepts, mechanisms and perspectives

I Lacal, R Ventura - Frontiers in molecular neuroscience, 2018 - frontiersin.org
Parents' stressful experiences can influence the offspring's vulnerability to many
pathological conditions, including psychopathologies, and their effects may even endure for …

[HTML][HTML] The epigenetic link between prenatal adverse environments and neurodevelopmental disorders

M Kundakovic, I Jaric - Genes, 2017 - mdpi.com
Prenatal adverse environments, such as maternal stress, toxicological exposures, and viral
infections, can disrupt normal brain development and contribute to neurodevelopmental …

Neurodevelopmental disorders and environmental toxicants: epigenetics as an underlying mechanism

NQV Tran, K Miyake - International journal of genomics, 2017 - Wiley Online Library
The increasing prevalence of neurodevelopmental disorders, especially autism spectrum
disorders (ASD) and attention deficit hyperactivity disorder (ADHD), calls for more research …

[HTML][HTML] The relationships between stress, mental disorders, and epigenetic regulation of BDNF

Z Miao, Y Wang, Z Sun - International journal of molecular sciences, 2020 - mdpi.com
Brain-derived neurotrophic factor (BDNF), a critical member of the neurotrophic family, plays
an important role in multiple stress-related mental disorders. Although alterations in BDNF in …

A comprehensive review of genetic and epigenetic mechanisms that regulate BDNF expression and function with relevance to major depressive disorder

B Hing, L Sathyaputri, JB Potash - American Journal of Medical …, 2018 - Wiley Online Library
Major depressive disorder (MDD) is a mood disorder that affects behavior and impairs
cognition. A gene potentially important to this disorder is the brain derived neurotrophic …

The epigenetic impacts of social stress: how does social adversity become biologically embedded?

VT Cunliffe - Epigenomics, 2016 - Future Medicine
Epigenetic mechanisms are implicated in the processes through which social stressors
erode health in humans and other animals. Here I review progress in elucidating the …

An ecologist's guide for studying DNA methylation variation in wild vertebrates

VN Laine, B Sepers, M Lindner… - Molecular Ecology …, 2023 - Wiley Online Library
The field of molecular biology is advancing fast with new powerful technologies, sequencing
methods and analysis software being developed constantly. Commonly used tools originally …

[HTML][HTML] Does prenatal stress shape postnatal resilience?–an epigenome-wide study on violence and mental health in humans

F Serpeloni, KM Radtke, T Hecker, J Sill… - Frontiers in …, 2019 - frontiersin.org
Stress during pregnancy widely associates with epigenetic changes and psychiatric
problems during childhood. Animal studies, however, show that under specific postnatal …