DNA methylation in stress and depression: from biomarker to therapeutics
Epigenetic mechanisms such as DNA methylation (DNAm) have been associated with stress
responses and increased vulnerability to depression. Abnormal DNAm is observed in …
responses and increased vulnerability to depression. Abnormal DNAm is observed in …
Stress across generations: DNA methylation as a potential mechanism underlying intergenerational effects of stress in both post-traumatic stress disorder and pre …
S Bhattacharya, A Fontaine, PE MacCallum… - Frontiers in Behavioral …, 2019 - frontiersin.org
Although most humans will experience some type of traumatic event in their lifetime only a
small set of individuals will go on to develop post-traumatic stress disorder (PTSD) …
small set of individuals will go on to develop post-traumatic stress disorder (PTSD) …
Caregiver maltreatment causes altered neuronal DNA methylation in female rodents
Negative experiences with a caregiver during infancy can result in long-term changes in
brain function and behavior, but underlying mechanisms are not well understood. It is our …
brain function and behavior, but underlying mechanisms are not well understood. It is our …
Hormones and human developmental plasticity
Natural selection favors the evolution of mechanisms that optimize the allocation of
resources and time among competing traits. Hormones mediate developmental plasticity …
resources and time among competing traits. Hormones mediate developmental plasticity …
[HTML][HTML] The epigenetics of animal personality
Animal personality, consistent individual differences in behaviour, is an important concept
for understanding how individuals vary in how they cope with environmental challenges. In …
for understanding how individuals vary in how they cope with environmental challenges. In …
Intrauterine exposure to maternal stress alters Bdnf IV DNA methylation and telomere length in the brain of adult rat offspring
DNA methylation (addition of methyl groups to cytosines) and changes in telomere length
(TTAGGG repeats on the ends of chromosomes) are two molecular modifications that result …
(TTAGGG repeats on the ends of chromosomes) are two molecular modifications that result …
Epigenetics and Early Life Stress: Experimental Brood Size Affects DNA Methylation in Great Tits (Parus major)
Early developmental conditions are known to have life-long effects on an individual's
behavior, physiology and fitness. In altricial birds, a majority of these conditions, such as the …
behavior, physiology and fitness. In altricial birds, a majority of these conditions, such as the …
Tracking the path of predator recognition in a predator-naive population of the pond snail
A Batabyal, K Lukowiak - Behavioral Ecology, 2023 - academic.oup.com
Organisms evolve adaptive strategies to adjust to rapidly changing environmental stressors.
Predation pressure is one of the strongest selective forces and organisms respond to …
Predation pressure is one of the strongest selective forces and organisms respond to …
A short pre-conception bout of predation risk affects both children and grandchildren
S Bhattacharya, PE MacCallum, M Dayma… - Scientific Reports, 2023 - nature.com
Traumatic events that affect physiology and behavior in the current generation may also
impact future generations. We demonstrate that an ecologically realistic degree of predation …
impact future generations. We demonstrate that an ecologically realistic degree of predation …
Pharmacological manipulation of DNA methylation normalizes maternal behavior, DNA methylation, and gene expression in dams with a history of maltreatment
The quality of parental care received during development profoundly influences an
individual's phenotype, including that of maternal behavior. We previously found that female …
individual's phenotype, including that of maternal behavior. We previously found that female …