[HTML][HTML] Antiviral Effect of 5′-Arylchalcogeno-3-aminothymidine Derivatives in SARS-CoV-2 Infection

AR Tucci, RM da Rosa, AS Rosa, O Augusto Chaves… - Molecules, 2023 - mdpi.com
The understanding that zidovudine (ZDV or azidothymidine, AZT) inhibits the RNA-
dependent RNA polymerase (RdRp) of SARS-CoV-2 and that chalcogen atoms can …

[HTML][HTML] Myrtucommulones and Related Acylphloroglucinols from Myrtaceae as a Promising Source of Multitarget SARS-CoV-2 Cycle Inhibitors

SC Mendonça, BA Gomes, MF Campos… - Pharmaceuticals, 2024 - mdpi.com
The LABEXTRACT plant extract bank, featuring diverse members of the Myrtaceae family
from Brazilian hot spot regions, provides a promising avenue for bioprospection. Given the …

Synthesis and evaluation of hybrid sulfonamide‐chalcones with potential antileishmanial activity

NS de Oliveira, LG de Souza… - Archiv der …, 2024 - Wiley Online Library
Leishmaniasis is an emerging tropical infectious disease caused by a protozoan parasite of
the genus Leishmania. In this work, the molecular hybridization between a trimethoxy …

Design, synthesis and evaluation of aurone and indanone derivatives as novel antitumor agents

B Xie, G Turdu, C Niu, HA Aisa - Medicinal Chemistry Research, 2024 - Springer
An aurone derivative HJ-1, was isolated from Coreopsis tinctoria in our previous work,
showed potential anti-hepatocellular carcinoma activity. From it, seventy-five compounds …

Exploring the Antiproliferative Potential of Morpholine‐Functionalized Aurones: Design, Synthesis, SAR, DFT, Hirshfeld Surface, 3D Energy Frameworks and …

G Kumar, B Saroha, B Kumari, S Ghosh… - …, 2024 - Wiley Online Library
In quest of generating a diverse array of potential cytotoxic candidates through molecular
hybridization approach, herein we have designed a library of forty‐one morpholine …

[HTML][HTML] Flavonoids as Inspiration for the Design and Synthesis of New Antiproliferative, Antiparasitic and Antiviral Compounds: An Account

GS Caleffi, AJM Silva, CD Netto… - Journal of the Brazilian …, 2024 - SciELO Brasil
Modified flavonoids of the sub-group of pterocarpans, 5-carba-pterocarpans, 5-
carbapterocarpens, 1-carba-isoflavanones, coumestans, and aurones were synthesized and …

[HTML][HTML] Crystal structure of (Z)-2-(4-((5-bromopentyl)oxy)benzylidene)-4,5,6-trimethoxybenzofuran-3(2H)-one, C23H25BrO6

HB Wang, LH Xu, JM Shi, Y Zhou… - … für Kristallographie-New …, 2023 - degruyter.com
Crystal structure of (Z)-2-(4-((5-bromopentyl)oxy)benzylidene)-4,5,6-trimethoxybenzofuran-3(2H)-one,
C23H25BrO6 Skip to content Should you have institutional access? Here's how to get it ... De …

[HTML][HTML] Crystal structure of (Z)-N-(4-(4-(4-((4,5,6-trimethoxy-3-oxobenzofuran-2(3H)-ylidene)methyl)phenoxy)butoxy)phenyl)acetamide, C30H31NO8

LH Xu, JM Shi, HB Wang, Y Zhou - Zeitschrift für Kristallographie …, 2023 - degruyter.com
Crystal structure of (Z)-N-(4-(4-(4-((4,5,6-trimethoxy-3-oxobenzofuran-2(3H)-ylidene)methyl)phenoxy)butoxy)phenyl)acetamide,
C30H31NO8 Skip to content Should you have institutional access? Here's how to get it …