Abstract Protein Arginine Methyltransferases (PRMTs) are a family of enzymes regulating
protein arginine methylation, which is a post-translational modification crucial for various …

Abstract Ethnopharmacological relevance The Bupi Yishen Formula (BYF) is a patented
Chinese herbal compound that has been long used to treat chronic kidney disease (CKD) in …

Abstract Background The Lauren classification of gastric tumors strongly correlates with
prognosis. The purpose of this study was to explore the specific molecular mechanism of …

Heat shock protein 27 is a type of molecular chaperone whose expression gets up-regulated
due to reaction towards different stressful triggers including anticancer treatments. It is …

Background: Methylsterol monooxygenase 1 (MSMO1), as a completely unique tumor
biomarker, plays a vital role in the malignant progression of various cancer. Until now, the …

Abnormal angiogenesis is a critical factor in tumor growth and metastasis, and protein
arginine methyltransferase 5 (PRMT5), a prominent type II enzyme, is implicated in various …

An altered expression of miR-143-3p has been previously reported in prostate cancer where
it is purported to play a tumor suppressor role. Evidence from other cancers suggests miR …

Lung adenocarcinoma is one of the most frequent tumor subtypes, involving changes in a
variety of oncogenes and tumor suppressor genes. Hydroxysteroid 17-Beta Dehydrogenase …

The balance of cell proliferation and size is key for the control of organ development and
repair. Moreover, this balance has to be coordinated within tissues and between tissues to …

The malignant tumor is a complex heterogeneous set of cells functioning in a no less
heterogeneous microenvironment. Like any dynamic system, cancerous tumors evolve and …