[HTML][HTML] Clinical and preclinical evidence for functional interactions of cannabidiol and Δ9-tetrahydrocannabinol

DL Boggs, JD Nguyen, D Morgenson… - …, 2018 - nature.com
The plant Cannabis sativa, commonly called cannabis or marijuana, has been used for its
psychotropic and mind-altering side effects for millennia. There has been growing attention …

[HTML][HTML] Gone to pot–a review of the association between cannabis and psychosis

R Radhakrishnan, ST Wilkinson, DC D'Souza - Frontiers in psychiatry, 2014 - frontiersin.org
Cannabis is the most commonly used illicit drug worldwide, with~ 5 million daily users
worldwide. Emerging evidence supports a number of associations between cannabis and …

[HTML][HTML] Endocannabinoid-mediated control of synaptic transmission

M Kano, T Ohno-Shosaku… - Physiological …, 2009 - journals.physiology.org
The discovery of cannabinoid receptors and subsequent identification of their endogenous
ligands (endocannabinoids) in early 1990s have greatly accelerated research on …

[HTML][HTML] The psychotomimetic effects of intravenous delta-9-tetrahydrocannabinol in healthy individuals: implications for psychosis

DC D'Souza, E Perry, L MacDougall… - …, 2004 - nature.com
Recent advances in the understanding of brain cannabinoid receptor function have renewed
interest in the association between cannabinoid compounds and psychosis. In a 3-day …

Cannabis-associated psychosis: Neural substrate and clinical impact

RM Murray, A Englund, A Abi-Dargham, DA Lewis… - …, 2017 - Elsevier
Prospective epidemiological studies have consistently demonstrated that cannabis use is
associated with an increased subsequent risk of both psychotic symptoms and …

Cannabidiol inhibits paclitaxel‐induced neuropathic pain through 5‐HT1A receptors without diminishing nervous system function or chemotherapy efficacy

SJ Ward, SD McAllister, R Kawamura… - British journal of …, 2014 - Wiley Online Library
Background and Purpose Paclitaxel (PAC) is associated with chemotherapy‐induced
neuropathic pain (CIPN) that can lead to the cessation of treatment in cancer patients even …

Cannabis and adolescent brain development

DI Lubman, A Cheetham, M Yücel - Pharmacology & therapeutics, 2015 - Elsevier
Heavy cannabis use has been frequently associated with increased rates of mental illness
and cognitive impairment, particularly amongst adolescent users. However, the …

Endocannabinoid-mediated synaptic plasticity in the CNS

V Chevaleyre, KA Takahashi, PE Castillo - Annu. Rev. Neurosci., 2006 - annualreviews.org
Abstract Changes in synaptic efficacy are thought to be crucial to experience-dependent
modifications of neural function. The diversity of mechanisms underlying these changes is …

Delta-9-tetrahydrocannabinol effects in schizophrenia: implications for cognition, psychosis, and addiction

DC D'Souza, WM Abi-Saab, S Madonick… - Biological …, 2005 - Elsevier
BACKGROUND: Recent advances in the neurobiology of cannabinoids have renewed
interest in the association between cannabis and psychotic disorders. METHODS: In a 3 …

The acute effects of cannabinoids on memory in humans: a review

M Ranganathan, DC D'Souza - Psychopharmacology, 2006 - Springer
Rationale Cannabis is one of the most frequently used substances. Cannabis and its
constituent cannabinoids are known to impair several aspects of cognitive function, with the …