Nitric oxide, carbon monoxide and hydrogen sulfide are three endogenous gasotransmitters
that serve a role in regulating normal and pathological cellular activities. They can stimulate …

Men demonstrate higher incidence and mortality rates of colorectal cancer (CRC) than
women. This study aims to explain the potential causes of such sexual dimorphism in CRC …

There is a pressing need for molecular targets and biomarkers in gastric cancer (GC). We
aimed at identifying aberrations in L-arginine metabolism with therapeutic and diagnostic …

Simple Summary Nitric oxide and arginine metabolism in colorectal cancer (CRC) holds
potential for therapeutic intervention. We hypothesized that it can be modulated by oxicams …

Colorectal cancer (CRC) is one of the major reasons of mortality in the worldwide. There is
clear evidence that some amino acids such as arginine can improve CRC and its …

Ductal carcinoma in situ (DCIS) is a severe breast disease. It generates little symptom and
may be neglected in prodromal stage. In this study, we developed a novel DCIS detection …

The L-Arginine/NO pathway is involved in carcinogenesis and immunity. Its diagnostic and
prognostic value in colorectal cancer (CRC) was determined using tandem mass …

Background Asymmetric dimethylarginine (ADMA), which is significantly elevated in the
plasma of cancer patients, is formed via intracellular recycling of methylated proteins and …

The L-arginine/NO pathway holds promise as a source of potential therapy target and
biomarker; yet, its status and utility in esophageal squamous cell carcinoma (ESCC) is …

Colorectal cancer (CRC) is the third most common cancer in the world, with increasing
morbidity and mortality. The current diagnosis and treatment plan rely on early detection and …