ACSL family: The regulatory mechanisms and therapeutic implications in cancer
J Quan, AM Bode, X Luo - European journal of pharmacology, 2021 - Elsevier
Accumulating evidence shows that deregulation of fatty acid (FA) metabolism is associated
with the development of cancer. Long-chain acyl-coenzyme A synthases (ACSLs) are …
with the development of cancer. Long-chain acyl-coenzyme A synthases (ACSLs) are …
Revealing the role of high-density lipoprotein in colorectal cancer
A Zeljkovic, J Vekic, M Mihajlovic, T Gojkovic… - International Journal of …, 2021 - mdpi.com
Colorectal cancer (CRC) is a highly prevalent malignancy with multifactorial etiology, which
includes metabolic alterations as contributors to disease development. Studies have shown …
includes metabolic alterations as contributors to disease development. Studies have shown …
Identification and validation of a nine-gene amino acid metabolism-related risk signature in HCC
Y Zhao, J Zhang, S Wang, Q Jiang… - Frontiers in cell and …, 2021 - frontiersin.org
Background: Hepatocellular carcinoma (HCC) is the world's second most deadly cancer,
and metabolic reprogramming is its distinguishing feature. Among metabolite profiling …
and metabolic reprogramming is its distinguishing feature. Among metabolite profiling …
Expression of lipid-metabolism genes is correlated with immune microenvironment and predicts prognosis in osteosarcoma
H Qian, T Lei, Y Hu, P Lei - Frontiers in cell and developmental …, 2021 - frontiersin.org
Objectives Osteosarcoma was the most popular primary malignant tumor in children and
adolescent, and the 5-year survival of osteosarcoma patients gained no substantial …
adolescent, and the 5-year survival of osteosarcoma patients gained no substantial …
Lycium barbarum polysaccharide modulates gut microbiota to alleviate rheumatoid arthritis in a rat model
W Lai, C Wang, R Lai, X Peng, J Luo - npj Science of Food, 2022 - nature.com
Rheumatoid arthritis (RA) seriously impairs the quality of life of sufferers. It has been shown
that Lycium barbarum polysaccharide (LBP), a natural active indigestible ingredient with …
that Lycium barbarum polysaccharide (LBP), a natural active indigestible ingredient with …
HCC subtypes based on the activity changes of immunologic and hallmark gene sets in tumor and nontumor tissues
J Gong, R Li, Y Chen, Z Zhuo, S Chen… - Briefings in …, 2021 - academic.oup.com
The prognostic role of adjacent nontumor tissue in hepatocellular carcinoma (HCC) patients
is still not clear. The activity changes of immunologic and hallmark gene sets in adjacent …
is still not clear. The activity changes of immunologic and hallmark gene sets in adjacent …
Identification and validation of a novel redox-related lncRNA prognostic signature in lung adenocarcinoma
J Ren, A Wang, J Liu, Q Yuan - Bioengineered, 2021 - Taylor & Francis
Lung adenocarcinoma (LUAD) is one of the main causes of cancer deaths globally. Redox
is emerging as a crucial contributor to the pathophysiology of LUAD, which can be regulated …
is emerging as a crucial contributor to the pathophysiology of LUAD, which can be regulated …
Hallmark-guided subtypes of hepatocellular carcinoma for the identification of immune-related gene classifiers in the prediction of prognosis, treatment efficacy, and …
C Guo, Y Tang, Z Yang, G Li, Y Zhang - Frontiers in Immunology, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC), accounting for~ 90% of all primary liver cancer, is a
prevalent malignancy worldwide. The intratumor heterogeneity of its causative etiology …
prevalent malignancy worldwide. The intratumor heterogeneity of its causative etiology …
Cinobufacini injection delays hepatocellular carcinoma progression by regulating lipid metabolism via SREBP1 signaling pathway and affecting macrophage …
M Wang, Y Li, S Li, T Wang, M Wang, H Wu… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Cinobufacini injection, an aqueous extract of the toad, is a
commonly used anti-tumor animal herbal medicine in clinical practice. It has the effects of …
commonly used anti-tumor animal herbal medicine in clinical practice. It has the effects of …
Lipid metabolism-related gene signature predicts prognosis and depicts tumor microenvironment immune landscape in gliomas
J Li, S Zhang, S Chen, Y Yuan, M Zuo, T Li… - Frontiers in …, 2023 - frontiersin.org
Background Glioma is the most common primary brain tumor in adults and accounts for
more than 70% of brain malignancies. Lipids are crucial components of biological …
more than 70% of brain malignancies. Lipids are crucial components of biological …