Vascular remodeling is a basic pathological process in various diseases characterized by
abnormal changes in the morphology, structure, and function of vascular cells, such as …

Thoracic aortic aneurysm (TAA) has a prevalence of 0.16–0.34% and an incidence of 7.6
per 100,000 person-years, accounting for 1–2% of all deaths in Western countries …

Senescence of vascular smooth muscle cells (VSMCs) contributes to aging-related
cardiovascular diseases by promoting arterial remodelling and stiffness. Ferroptosis is a …

BACKGROUND: Hemangioblasts are mesoderm-derived multipotent stem cells for
differentiation of all hematopoietic and endothelial cells in the circulation system. However …

Triple-negative breast cancer (TNBC) stands as the breast cancer subtype with the highest
recurrence and mortality rates, with the lungs being the common site of metastasis. The …

Coronary artery disease (CAD) is the most prevalent cardiovascular disease worldwide,
resulting in myocardial infarction (MI) and even sudden death. Following percutaneous …

Abstract Chronic Kidney Disease (CKD) has emerged as a global public health concern,
with its primary pathological basis being Renal Fibrosis (RF), crucial to halt its progression to …

Background Omental metastasis is the major cause of ovarian cancer recurrence and
shortens patient survival, which can be largely attributed to the dynamic evolution of the …

Aortic aneurysm (AA) and dissection (AD) are aortic diseases caused primarily by medial
layer degeneration and perivascular inflammation. They are lethal when the rupture …

Systemic sclerosis (SSc) is an autoimmune disease characterized by vasculopathy, aberrant
immune activation, and extensive tissue fibrosis of the skin and internal organs. Because of …