[HTML][HTML] Small RNA modifications: regulatory molecules and potential applications

Q Xiong, Y Zhang - Journal of Hematology & Oncology, 2023 - Springer
Small RNAs (also referred to as small noncoding RNAs, sncRNA) are defined as polymeric
ribonucleic acid molecules that are less than 200 nucleotides in length and serve a variety of …

Sperm RNA-mediated epigenetic inheritance in mammals: challenges and opportunities

Q Chen - Reproduction, Fertility and Development, 2022 - CSIRO Publishing
Emerging evidence now shows that in addition to delivering a haploid DNA, the mammalian
sperm also carry various types of RNAs that respond to the paternal environment, which can …

[HTML][HTML] METTL1 mediated tRNA m7G modification promotes leukaemogenesis of AML via tRNA regulated translational control

P Zhao, L Xia, D Chen, W Xu, H Guo, Y Xu… - … Hematology & Oncology, 2024 - Springer
Background RNA modifications have been proven to play fundamental roles in regulating
cellular biology process. Recently, maladjusted N7-methylguanosine (m7G) modification …

[HTML][HTML] Altered landscape of total RNA, tRNA and sncRNA modifications in the liver and spleen of mice infected by Toxoplasma gondii

XX Zhang, YZ Sun, W Wang, Y Gao… - PLOS Neglected …, 2024 - journals.plos.org
Background Pathogens can impact host RNA modification machinery to establish a
favorable cellular environment for their replication. In the present study, we investigated the …

Expression profiles of circular RNAs in spermatozoa from aging men

Q Zhou, A Liu, H Ji, J Ji, J Sun, Z Ling, G Li… - Molecular Biology …, 2023 - Springer
Background Advanced paternal age (APA) is associated with decreased fertility, but the
mechanism underlying APA remains unknown. CircRNAs have been reported to be ideal …

5-methylcytidine effectively improves spermatogenesis recovery in busulfan-induced oligoasthenospermia mice

C Wang, T Ye, J Bao, J Dong, W Wang, C Li… - European Journal of …, 2024 - Elsevier
The function and regulatory mechanisms of 5-methylcytidine (m 5 C) in oligoasthenospermia
remain unclear. In this study, we made a mouse model of oligoasthenospermia through the …

Dynamic RNA methylation modifications and their regulatory role in mammalian development and diseases

W Yang, Y Zhao, Y Yang - Science China Life Sciences, 2024 - Springer
Among over 170 different types of chemical modifications on RNA nucleobases identified so
far, RNA methylation is the major type of epitranscriptomic modifications existing on almost …

[PDF][PDF] Role and Mechanism of Epigenetic Regulation in the Aging of Germ Cells: Prospects for Targeted Interventions

XC Huang, YN Jiang, HJ Bao, JL Wang, RJ Lin… - Aging and …, 2025 - researchgate.net
In modern times, a notable trend toward delayed childbearing has been observed in most
developed countries. As a result, sperm aging and quality loss, as well as premature ovarian …

'Human and Animal Model Reproductive Epigenetics' special collection:(un) intended marks on fertility

M Boiani, FE Duncan - Molecular human reproduction, 2023 - academic.oup.com
Molecular Human Reproduction (MHR) prides itself on taking forward the successful
initiative of open calls for papers, following the inaugural call of Spring 2017 ('In vitro …