Cancer is one of the leading causes of death globally, around 10 million deaths are reported
every year due to cancer. Some clinically approved anticancer drugs play a riveting role in …

Chalcones are a fascinating and well‐studied group of organic molecules. Synthesis of
chalcones has been one of the essential areas of organic synthesis over the last few …

In the present study we designed and synthesized 26 coumarin clubbed chalcone hybrids (1–
13 and 14–26) in good yields (54.32–74.25%) and further tested for their antimicrobial and …

2′-hydroxy-chalcones are naturally occurring compounds with a wide array of bioactivity. In
an effort to delineate the structural features that favor antioxidant and lipoxygenase (LOX) …

Chalcones are α, β unsaturated aromatic ketones having enone moiety and exhibit a wide
array of pharmaceutical and biological activities. Chalcones possess a wide range of …

A series of novel multi-substituted coumarin derivatives were synthesized, spectroscopically
characterized, and evaluated for their antioxidant activity, soybean lipoxygenase (LOX) …

Developing improved enzyme inhibitors is an effective therapy to counter various diseases.
Aiming to build up biologically active templates, a new series of bis-diazoles conjugated with …

Abstract A new series of 1, 3, 5-trisubstituted 2-pyrazoline derivatives (3a–l) are synthesized
in good to excellent yields from the corresponding chalcones (1a–h) and acid hydrazides …

Antioxidants are radical scavengers that have been proposed to be involved in many
pathological conditions, from aging to degenerative disorders. The aim of the present study …

In this work, the privileged scaffold of 4-hydroxy-2quinolinone is investigated through the
synthesis of carboxamides and hybrid derivatives, as well as through their bioactivity …