Genetic variation, which is generated by mutation, recombination and gene flow, can reduce
the mean fitness of a population, both now and in the future. This 'genetic load'has been …

Nearly all genetic variants that influence disease risk have human-specific origins; however,
the systems they influence have ancient roots that often trace back to evolutionary events …

Horse domestication revolutionized warfare and accelerated travel, trade, and the
geographic expansion of languages. Here, we present the largest DNA time series for a non …

During the last centuries, humans have transformed global ecosystems. With their temporal
dimension, herbaria provide the otherwise scarce long‐term data crucial for tracking …

Ancient DNA (aDNA) has added a wealth of information about our species' history, including
insights on genetic origins, migrations and gene flow, genetic admixture, and health and …

" Sometime before 15,000 years ago, a band of hunter-gatherers arrived in Northeast Asia.
They continued east, becoming the first people to set foot in the Americas. They soon found …

Vitamin D 3 is produced non-enzymatically when the cholesterol precursor 7-
dehydrocholesterol is exposed to UV-B, ie, evolutionary the first function of the molecule was …

Anticipating and addressing the social implications of scientific work is a fundamental
responsibility of all scientists. However, expectations for ethically sound practices can evolve …

Although ancient DNA data have become increasingly more important in studies about past
populations, it is often not feasible or practical to obtain high coverage genomes from poorly …

The rise of ancient genomics has revolutionised our understanding of human prehistory but
this work depends on the availability of suitable samples. Here we present a complete …